轻度认知功能障碍患者情绪记忆改变特征的研究

目的:探讨轻度认知功能障碍(MCI)患者情绪记忆效价的改变特征。方法:建立情绪记忆的神经认知心理学试验方法,检测教育水平等相匹配的22例MCI患者(MCI组)和22例健康对照(对照组)的情绪记忆。结果:与对照组[正性(63.80±6.92)%、负性(57.60±6.07)%]相比,MCI组对正性[(54.00±6.80)%]和负性[(53.07±5.92)%]情绪图片再认率差异均有统计学意义(t=-5.53、-2.92,P<0.05);且反应时间延长,2组的中性情绪图片再认率(t=-0.38,P>0.05)及反应时间(t=1.48,P>0.05)差异均无统计学意义。MCI组对正性、负性与中性情绪图片再认正确率(F=6.27,P<0.05)及反应时间(F=3.74,P<0.05)差异均有统计学意义,而正性与负性差异无统计学意义(P>0.05);对照组对正性、中性和负性图片再认正确率(F=39.13,P<0.05)及反应时间(F=16.48,P<0.05)差异均有统计学意义。2组对情绪图片的效价评定无统计学差异(P>0.05)。结论:MCI患者存在情绪记忆的受损及反应时间延长,且情绪效价"正向"选择性偏向受损。

Characteristics of Emotional Memory Changes in Patients with Mild Cognitive Impairent

Objective: To explore the characteristics of emotional memory changes in patients with mild cognitive impairment (MCI). Methods: A neuro-cognitive psychology test method for emotional memory was set, and the emotional memory of 22 MCI patients (MCI group) and 22 healthy controls (control group) matched by educational level were examined. Results: Compared with the control group [positive (63.80±6.92)%, negative (57.60±6.07)%, images recognition in the MCI group [positive (54.00±6.80)%, negative (53.07±5.92)%]had been impaired (t=-5.53,-2.92, P<0.05), but there were no significant difference in neutral stimuli (t=-0.38, P> 0.05) and reaction time (t=1.48, P>0.05). There were significant differences in recognition accuracy of positive, negative and neutral emotional pictures (F=6.27, P<0.05) and reaction time (F=3.74, P<0.05) of MCI group, and there was no significant difference between positive and negative (P>0.05). There were significant differences in recognition accuracy of positive, negative and neutral emotional pictures (F=39.13, P<0.05) and reaction time (F= 16.48, P<0.05) of control group. However, there was no significant difference in their rating of valence of the images. Conclusion: Emotional memory is impaired in MCI patients and reaction times were significantly slower, and emotional valence“positive”selective bias is impaired.