太行山食管癌高发区10561例食管/贲门癌患者ABO血型分布特征及体重指数

目的：探讨太行山食管癌高发区食管/贲门癌患者ABO血型分布特征及体重指数与食管/贲门癌关系。方法：对太行山食管癌高发区多家医院病例进行回顾性调查,收集10 561例食管/贲门癌患者年龄、性别、籍贯、ABO血型及身高、体重等资料,计算体重指数（BMI=kg/m^2）,并对ABO血型的分布及食管/贲门癌患者各级BMI的构成比进行统计学分析。结果：①太行山食管癌高发区食管癌和贲门癌患者ABO血型分布特征均为B〉O〉A〉AB,且不同性别之间无差异（P〉0.05）;②该地区食管癌和贲门癌患者中正常体重者所占比例均为最多,低体重和超重者次之,肥胖者最少。但是女性食管癌患者中Ⅰ级BMI所占比例低于贲门癌相应BMI所占比例（22%,69/310vs.27%,18/66）,Ⅱ级BMI所占比例高于贲门癌相应BMI所占比例（54%,169/310vs.49%,32/66）。结论：B型血者患食管/贲门癌的风险较大,AB型血者患食管/贲门癌的风险较低。体重过低的女性患食管癌的风险较其患贲门癌的风险大,而体重在正常范围的女性患贲门癌的风险较大。

Distribution of ABO blood-group and body mass index in 10561 patients with esophageal and gastric cardia cancers from high-incidence area around Taihang Mountain

Objective： To characterize the ABO blood-group and Body Mass Index and esophageal and gastric cardia cancers in high-incidence areas around Taihang Mountain. Methods： A total of 10 561 patients with esophageal squamous cell carcinoma （SCC） and gastric cardia adenocarcinoma （GCA） and all from high-incidence areas around Taihang Mountain. Data on age, gender, native place, ABO blood groups, weight, and height of the patients were collected from hospital records. Body mass index was calculated with weight in kilograms divided by the square of body height in meters （kg/m^2）. All the data were treated by χ^2. Results： The distribution of ABO blood groups in patients with SCC （B 〉 O 〉 A 〉 AB） was similar to the patients with GCA in Taihang Mountain area, and the percentage of ABO blood groups in SCC/GCA between male and female was no difference （P 〉 0.05）. Normal BMI was the main pattern for both SCC and GCA. However, the percentage of female SCC with low BMI （22% , 69/310 ） was lower than in GCA （27% , 18/66）, and the percentage of female SCC with normal BMI （54% , 169/30） was higher than in GCA （49%, 32/66）. Conclusion： The present results indicate that blood type B was in high risk for SCC/GCA, and blood type AB was in low risk form SCC/GCA. Underweight female showed a high risk for SCC, the female within normal range of weight was in high risk for GCA.