| 瑞波西汀对首发精神分裂症患者认知功能的影响 |
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| 引用本文： | 孙健,刘勇,王红霞,王宏升.瑞波西汀对首发精神分裂症患者认知功能的影响[J].中国实用医药,2011,6(28):4-6. |
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| 作者姓名： | 孙健 刘勇 王红霞 王宏升 |
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| 作者单位： | 河南省驻马店市精神病院,463000 |
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| 摘 要： | 目的观察瑞波西汀对首发精神分裂症患者认知功能的影响。方法采用随机、双盲对照法,将120例首发精神分裂症患者平均分为研究组(瑞波西汀+氟哌啶醇)和观察组(氟哌啶醇+安慰剂)。在治疗前,治疗后4、8、12周末分别以阳性症状和阴性症状量表(PNASS)和不良反应量表(TESS)评定疗效和不良反应,韦氏记忆量表(WMS)评定治疗前后患者认知功能的改变。结果治疗12周后,研究组的韦氏记忆量表的再认、联想及记忆商(MQ)为:(9.5±2.3)、(10.8±1.7)、(103.7±12.9);观察组分别为(8.4±1.5)、(9.1±1.6)、(90.5±11.9),两组差异有统计学意义(P<0.05)。PANSS总分、阴性因子分及一般精神病理症状分比治疗前明显降低,治疗后4、8、12周末TESS评分,研究组均低于观察组,且治疗后低于治疗前,差异均有统计学意义(P<0.05)。结论瑞波西汀对首发精神分裂症患者认知功能有明显改善,且不良反应减少。
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| 关 键 词： | 精神分裂症 认知功能 瑞波西汀 氟哌啶醇 |
Effect of Reboxetine combined with Haloperidol in the treatment of first-episode schizophrenia on cognition function |
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| SUN Jian,LIU Yong,WANG Hong-xia,et al..Effect of Reboxetine combined with Haloperidol in the treatment of first-episode schizophrenia on cognition function[J].China Practical Medical,2011,6(28):4-6. |
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| Authors: | SUN Jian LIU Yong WANG Hong-xia |
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| Institution: | SUN Jian,LIU Yong,WANG Hong-xia,et al.The Mental Hospital of Zhumadian,463000,China |
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| Abstract: | Objective To observe the cognition function of Reboxetine combined with Haloperidol in the treatment of schizophrenia.Methods Being used the vendom control stady,120 in-patients with chyonic schizophreaia were divided into study gooup(Reboxetine and Haloperidol) and control group(Haloperidol and comfort).Effects and side effects were assessed with PANSS and TESS respectively WMS were evaluated before treatment and after 4.8.12 weeks treatment.Results After treating 12 turnovers,The Wei surname of the resear... |
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| Keywords: | Schizophrenia Cognition function Reboxetine Haloperidol |
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