| 血尿酸与2型糖尿病患者下肢血管病变的关系 |
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| 引用本文： | 邱代伟. 血尿酸与2型糖尿病患者下肢血管病变的关系[J]. 中国实用医药, 2011, 6(28): 11-12 |
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| 作者姓名： | 邱代伟 |
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| 作者单位： | 重庆南川宏仁医院内分泌科,401326 |
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| 摘 要： | 目的 探讨2型糖尿病(T2DM)患者血尿酸(BUA)与下肢血管病变的关系,探讨其在2型糖尿病下肢血管病变中的作用.方法 82例2型糖尿病患者,根据踝肱指数(ABI)分为外周动脉疾病组(PAD)组和非外周动脉疾病组(NPAD),同期选择重庆南川宏仁医院健康体检35例作为正常对照(NC)组,采用常规生化学方法测定BUA水平,并分析BUA与ABI、WHR、血糖血压、HOMA-IR等相关代谢指标的关系.结果 PAD组、NPAD组BUA水平均高于NC组(P<0.01);PAD组BUA水平显著高于NPAD组(P<0.01).2型糖尿病患者ABI与WHR、BUA、FBG和HOMA-IR呈负相关(r=0.220、0.369、0.281、0.347,P<0.01或<0.05).HOMA.IR和BUA为影响T2DM患者ABI的独立相关因素.结论 BUA与T2DM患者ABI有密切相关,可能在T2DM下肢血管病变的发生发展中起着重要作用.
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| 关 键 词： | 血尿酸 2型糖尿病 下肢血管病变 |
Association between blood uric acid and lower limb vasculopathy in patients with type 2 diabetes |
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| QIU Dai-wei. Association between blood uric acid and lower limb vasculopathy in patients with type 2 diabetes[J]. China Practical Medical, 2011, 6(28): 11-12 |
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| Authors: | QIU Dai-wei |
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| Affiliation: | QIU Dai-wei.Department of Endocrinology,Hong Ren hospital of nanchuan in Chongqing,Chongqing 401326,China |
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| Abstract: | Objective To investigate the relationship of blood uric acid(BUA) with lower limb vasculopathy in type 2 diabetic patients and explore on roles of BUA in lower limb vasculopathy of type 2 diabetes mellitus.Methods 82 patients with type 2 diabetes mellitus were divided into peripheral arterial disease(PAD) group and non-peripheral arterial disease(NPAD) group according to the ankle brachial index(ABI),and meanwhile choose 35 patients of health examination as control groups(NC group).BUA levels were measured ... |
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| Keywords: | Blood uric acid Type 2 Diabetes mellitus Lower limb vasculopathy |
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