| 血清维生素A与儿童1型糖尿病的相关性探讨 |
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| 引用本文： | 陈永兴,卫海燕,李春枝,王凌飞,罗淑颖,王会贞.血清维生素A与儿童1型糖尿病的相关性探讨[J].中国实用医药,2011,6(29):17-18. |
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| 作者姓名： | 陈永兴 卫海燕 李春枝 王凌飞 罗淑颖 王会贞 |
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| 作者单位： | 郑州市儿童医院内分泌科,郑州,450052 |
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| 基金项目： | 郑州市科技局基金赞助项目 |
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| 摘 要： | 目的 初步探讨血清维生素A水平与儿童1型糖尿病(T1DM)关系,了解糖化血红蛋白(HbAlc)、血清空腹C-肽与血清维生素A的相关性.方法 选取32例T1DM患儿为T1DM组,28例健康体检儿童为对照组,用微量荧光方法 检测两组血清维生素A水平,用化学发光法、激光散射比浊法分别测定32例T1DM患儿血清C-肽、HbAlc.结果 T1DM组血清维生素A水平明显低于对照组(P<0.01);T1DM组血清维生素A水平与空腹血清C-肽水平呈正相关(r:0.356,P<0.05),与HbAlc呈负相关(r=-0.394,P<0.05).结论 T1DM患儿体内存在维生素A缺乏,维生素A水平低下可能与T1DM的发生有关.
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| 关 键 词： | 维生素A 糖尿病 1型 儿童 |
The relationship between serum concentration of vitamin A and type 1 diabetes mellitus in children |
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| CHEN Yong-xing,WEI Hai-yan,LI Chun-zhi,et al..The relationship between serum concentration of vitamin A and type 1 diabetes mellitus in children[J].China Practical Medical,2011,6(29):17-18. |
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| Authors: | CHEN Yong-xing WEI Hai-yan LI Chun-zhi |
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| Institution: | CHEN Yong-xing,WEI Hai-yan,LI Chun-zhi,et al.Department of Endocrinology of Zhengzhou Childern's Hospital,Zhengzhou 450052,China |
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| Abstract: | Objective To explore the relationship between serum concentration of vitamin A and type 1 diabetes mellitus in children.Methods Totally 32 children with T1DM were taken as T1DM group,and 28 healthy children as normal control group.The serum concentration of vitamin A was determined by the method of micro-flourescence,and the serum level of C-peptide and the level of HbA1c were determined by the methods of chemoluminescence and laser nephelometry,respectively.Results The level of vitamin A in T1DM group was ... |
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| Keywords: | Vitamin A Diabetes mellitus Type 1 Child |
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