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High abundances of neurotrophin 3 in atopic dermatitis mast cell |
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| Authors: | David Quarcoo Tanja C Fischer Nora Peckenschneider David A Groneberg and Pia Welker |
| Institution: | (1) Institute of Occupational Medicine, Charit? – Universit?tsmedizin Berlin, Free University and Humboldt University, D-14195 Berlin, Germany;(2) Department of Dermatology and Allergy, Charit? – Universit?tsmedizin Berlin, Free University and Humboldt University, D-10115 Berlin, Germany;(3) Institute of Anatomy, Charit? – Universit?tsmedizin Berlin, Free University and Humboldt University, D-10115 Berlin, Germany |
| Abstract: | BackgroundNeurotrophin 3 (NT-3) is a member of the neurotrophin family, a group of related proteins that are known to regulate neuro-immune interactions in allergic diseases. Their cellular sources and role in the recruitment of mast cell precursors in atopic dermatitis have not been characterized in detail so far. |
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