| 人参二醇组与三醇组皂甙对大鼠心室肌细胞钙通道阻滞作用的单通道分析 |
| |
| 引用本文： | 张文杰,钟国赣,江岩,王小明,王中峰.人参二醇组与三醇组皂甙对大鼠心室肌细胞钙通道阻滞作用的单通道分析[J].中国药理学报(英文版),1994(2). |
| |
| 作者姓名： | 张文杰 钟国赣 江岩 王小明 王中峰 |
| |
| 作者单位： | 白求恩医科大学生理教研室，白求恩医科大学生理教研室，Central Laboratory of physiology of Physiology，Norman Bethune University of Medical Sciences，Changchun 130021 China，Central Laboratory of physiology of Physiology，Norman Bethune University of Medical Sciences，Changchun 130021 China，Central Laboratory of physiology of Physiology，Norman Bethune University of Medical Sciences，Changchun 130021 China 长春 130021 中国，长春 130021 中国 |
| |
| 摘 要： | 分离Wistar大鼠乳鼠的心室肌细胞。向培养基中分别加入人参二醇组皂甙1500 μg·ml~(-1),人参三醇组皂甙300μg·ml~(-1),维拉帕米37.5 μg·ml~(-1)或BAY k 8644 5 μmol·L~(-1)。用斑片钳的连细胞电压钳法,记录加药前后L,T,B三型钙通道的单通道活动。确证了这两组人参皂甙的钙通道阻滞作用,其作用机制在于使钙通道的开放时间缩短与开放概率减
|
| 关 键 词： | 人参 皂甙 培养的细胞 心肌 斑片钳 维拉帕米 BAY k 8644 电生理学 |
Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cul- tured rat ventricular myocytes |
| |
| ZH'ANG Wen-Jie,ZHONG Guo-Gan,JIANG Yan WANG Xino-Ming,WANG Zhong-Feng.Single channel analysis on calcium channel blockade action of panaxadiol and panaxatriol saponins on cul- tured rat ventricular myocytes[J].Acta Pharmacologica Sinica,1994(2). |
| |
| Authors: | ZH'ANG Wen-Jie ZHONG Guo-Gan JIANG Yan WANG Xino-Ming WANG Zhong-Feng |
| |
| Abstract: | |
| |
| Keywords: | ginseng saponins cultured cells myocardium patch clamp verapamil BAY k 8644 electrophysiology |
| 本文献已被 CNKI 等数据库收录！ |
