轻度认知功能损害患者负性情绪与脑缺血指数研究

目的:探讨轻度认知功能损害(MCI)患者负性情绪与脑缺血指数的关系。方法:用Zung抑郁自评量表(SDS)、Zung焦虑自评量表(SAS)和Hachinski缺血指数量表(HIS)对MCI组(98例MCI患者)进行测试,并与国内常模或对照组(98名健康人)比较。结果:MCI组存在明显抑郁、焦虑,SDS和SAS评分均显著高于国内常模(P<0.05,0.01);MCI组HIS评分显著高于对照组(1.58±0.96)分,(0.64±0.74)分,P<0.05];SDS及SAS评分与HIS评分呈显著正相关。结论:MCI患者常伴有负性情绪,慢性缺血可能是MCI的高危因素,MCI患者脑缺血越明显则抑郁和焦虑症状越重。

A Study on Negative Emotion and Ischemic Score in Patients with Mild Cognitive Impairment

Objective:To explore relationship between negative emotion and ischemic score in patients with mild cognitive impairment(MCI).Methods:Ninety-eight MCI patients and 98 normal controls were evaluated with Self-rating Depression Scale of Zung(SDS)、Self-rating Anxiety Scale of Zung(SAS)and Hachinski Ischemic Score(HIS).Results:Depression and anxiety were very common in the MCI patients.The scores of SDS and SAS were significantly increased in the patients.The HIS score of MCI patients was significantly higher than that of the controls.There is a correlation between the scores of SDS,SAS and HIS score.Conclusion:Negative emotion was very common in patients with MCI.Chronic ischemia may be a highly risky factor of MCI.Severity of depression and anxiety was closely related to ischemia.