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化学髓核溶解术治疗腰椎间盘突出症
引用本文:庄文权,陈伟,杨建勇. 化学髓核溶解术治疗腰椎间盘突出症[J]. 中山大学学报(医学科学版), 2000, 21(1): 60-62
作者姓名:庄文权  陈伟  杨建勇
作者单位:庄文权(中山医科大学附属第一医院放射科, 广东 广州510080)
摘    要:目的探讨化学髓核溶解术的一种新的穿刺方法,用于治疗破裂型腰椎间盘突出症。方法采用经背后入路直接穿刺椎间盘脱出部位,用600单位的胶原酶溶解脱出的椎间盘组织治疗破裂脱出型腰椎间盘突出症。本组治疗43例临床确诊为破裂脱出型腰椎间盘突出症,并随访半年至2年。结果采用本穿刺方法治疗43例腰椎间盘脱出患者,治愈27例,治愈率为63%,有效11例,有效率为88%,无椎间盘变窄和退行性变等并发症出现。结论经背后入路直接穿刺脱出的椎间盘组织行胶原酶溶解术是一种操作简单、安全、有效的新方法,可减少并发症的发生。

关 键 词:化学髓核溶解术; 脊椎穿刺; 椎间盘移位/治疗;椎间盘切除术,经皮/方法
文章编号:1000-257X(2000)01-0060-03
修稿时间:1999-09-21

Treatment of SequesteredLumbar Disk Herniation with Chemonucleolysis
ZHUANG Wen quan,CHEN Wei,YANG Jian yong,ZHANG Ling,HUANG Yong hui. Treatment of SequesteredLumbar Disk Herniation with Chemonucleolysis[J]. Journal of Sun Yatsen University(Medical Sciences), 2000, 21(1): 60-62
Authors:ZHUANG Wen quan  CHEN Wei  YANG Jian yong  ZHANG Ling  HUANG Yong hui
Abstract:Objective To study a new method of puncture for the treatment of sequestered lumbar disk herniation with chemonucleolysis. Methods Forty three patients with clinically confirmed sequestered lumbar disk herniation underwent the new interventional procedure, which implied the direct via back puncture and a subsequent injection of 600 units of collagenase into the herniated lumbar disk tissue. All the patients were followed up for from half a year to 2 years. Results Of the forty three patients receiving this remedy, 27 were cured(63%) and 11 were regarded as being effective. The total effective rate was 88%. No narrowing of intervertebral space or degeneration of intervertebral disk was noted. Conclusion Via back routepuncture chemonucleolysis is a simple, safe and effective method for the treatment of sequestered lumbar disk herniation with far less complication.
Keywords:chemonucleolysis  spinal puncture  intervertebral disk displacement/therapy  diskectomy   percutaneous/methods
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