XU Lie-ming,ZHU Jian-liang,LIU Cheng LIU Ping,LU Gang,XUE Hui-ming HU Yi-yang and HONG Jia-he (Institute of Liver Diseases,Shanghai Academy of Traditional Chinese Medicine,Shanghai (200032
1. Institute of Liver Diseases, Shanghai Academy of Traditional Chinese Medicine, 200032, Shanghai
Abstract:
Objective: To evaluate the effect of Semen Persicae combined with cultured Cordyceps on Reversing Capillarization of Sinusoids in patients with hepato-cirrhosis. Methods: Forty-four patients were treated for 3 months, the clinical and pathological effects were observed. Results: Patients were improved clinically.Pathological examination on liver biopsy of 6 patients also showed improvement in of capillarization of sinusoid,which mainly manifested by reduction of enlarged interhepatocellular spaces and collagen fiber in it, increase of lipid droplets within fat-storing cells (FSC), and decrease of proliferation of Kupffer cells. Conclusion: The combined treatment used could reverse the capillarization of sinusoid, and the mechanism might be related with its inhibition on activity and function of FSC.