膀胱癌术前活检较术后病理分级低估的临床分析

目的：研究膀胱癌术前活检较术后病理分级低估可能的原因。方法：总结75例术前膀胱镜活检诊断膀胱癌，术后病理检查资料完整的患者分级进行比较分析。结果：75例患者术前活检病理分级G1 22例，G2 49例，G3 4例；术后标本病理分级为G1 2例，G2 26例，G3 47例；术前活检病理分级与术后标本病理分级一致22例（29．33％），活检低估分级50例（66.67％），高估分级3例（4．00％），三组比较存在显著性差异（P〈0．01）。结论：膀胱癌的术前活检与术后病理分级比较存在低估现象，充分重视低估现象可避免治疗不足的发生。

Clinical study of underestimation the histologic grade by preoperative biopsy compared with postoperative specimen in bladder carcinoma

Objective：To study the histologic grade between biopsy and postoperative specimen in bladder transition cell carcinoma and explore the reasons of underestimation. Methods ： Seventy five cases of bladder transition cell carcinoma were summarized and classified by biopsy preoperative and postoperative specimen. Results： Among 75 patients cases ,49 cases ,4 cases were G1 , G2 , G3 by biopsy preoperatively, respectively, and 2 cases ,26 cases ,47 cases were G1 , G2, G3 by postoperative specimen. There were 50 cases （66.67 % ）underestimated the histologic grade by biopsy preoperatively, 3 cases （4.00%）overestimated preoperatively, 22 cases （29.33%）accord （P 〈 0.01 ）. Conclusion： There is the underestimation phenomenon in histologic grade between biopsy and postoperative specimen in bladder transition cell carcinoma diagnosis and we should pay attention to this phenomenon.