中西医结合治疗成人原发性肾病综合征50例

目的]观察采用中西医结合方法治疗原发性肾病综合征的临床疗效。方法]全部96例病人随机分为中西医组(n=50)和西医组 (n=46)。西医组给予常规治疗,中西组在此基础上应用中药治疗,均用活血化瘀治疗 (血府逐瘀汤加减或血府逐瘀胶囊加减)。结果]中西医组总有效率为86 9%,西药组总有效率为53 3%,两组比较有显著性差异(P<0.01)。两组均有不同程度的糖皮质激素或/和细胞毒性药物副作用,中西医组副作用发生明显轻于西医组,两组比较有显著性差异(P<0.01)。结论]采用中西医结合方法治疗成人原发性肾病综合征可以提高疗效,降低副作用发生。

Treating adult primary nephropathy syndrome in 50 cases by integrated traditional Chinese and western medicine

Objective] To investigate the clinical effect of integrated traditional Chinese and Western medicine on adult primary nephropathy syndrome.Methods] All patients were randomly divided into integrated traditional Chinese and Western medicine (ITCWM) group (n=50) and Western medicine (WM) group (n=46). Routine treatment was given in WM group.While routine and TCM treatment were in ITCWM group.In this group the patient was treated by Xuefu Zhuyu method (the variation of Xufu Zhuyu Decoction or Capsule).Results] The overall effective rate in ITCWM group was 86.9% and in WM group was 53.3% with obvious difference between these two groups (P<0.01). Glucocorticoid or/and cell toxicity as drug side effects were presented in both both groups with different degrees.It was less servere ITCWM group than that in WM group.There was marked difference between the two groups (P<0.01).Conclusion] Treating adult primary nephropathy syndrome by integrated traditional Chinese and Western medicine can improve the clinical effect and decrease the side effect.