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复方益肾软胶囊提取工艺研究
引用本文:刘毅. 复方益肾软胶囊提取工艺研究[J]. 天津中医药大学学报, 2007, 24(5): 416-418
作者姓名:刘毅
作者单位:天津大学药物科学与技术学院, 天津, 300072
基金项目:天津市科技发展计划项目(033187511)。
摘    要:[目的]优选复方益肾软胶囊的最佳提取工艺。[方法]采用正交设计法,以马钱素的提取转移率为评价指标,对乙醇浓度、用量及渗漉速度等影响因素进行研究。[结果]最佳提取工艺为A3B3C1,即用70%乙醇进行渗漉,滴速为3.0mL/(min·kg),收集药材量8倍体积的渗漉液。[结论]本方法优选得到的工艺稳定可行。

关 键 词:复方益肾软胶囊  提取工艺  正交实验  马钱素
收稿时间:2007-02-02

Extracting technology for compound Yishen soft capsule
LIU Yi. Extracting technology for compound Yishen soft capsule[J]. Journal of Tianjin University of Traditonal Chinese Medicine, 2007, 24(5): 416-418
Authors:LIU Yi
Affiliation:The Pharmaceutical Science and Technology College of Tianjin University, Tianjin 300072, China
Abstract:[Objective] To explore the optimum extracting conditions for compound Yishen (tonifying the kidney) soft capsule.[Methods] The orthogonal design was taken for the optimization of ethyl alcohol and percolate speed with the content of loganin determined by RP-HPLC.[Results] The optimum extracting conditions were A3B3C1,that is percolating with 70% EtoH,the percolate speed with 3.0 mL/(min·kg),collecting the amount of percolate 8 times.[Conclusions] The optimum extracting procedure is reasonable and stable.
Keywords:compound Yishen soft capsule  extracting conditions  orthogonal test  loganin
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