| 用均匀设计优选苦参半仿生提取法工艺条件 |
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| 引用本文： | 王英姿,惠建国,张兆旺,孙秀梅.用均匀设计优选苦参半仿生提取法工艺条件[J].天津中医药大学学报,2010,27(1):66-68. |
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| 作者姓名： | 王英姿 惠建国 张兆旺 孙秀梅 |
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| 作者单位： | 北京中医药大学中药学院, 北京, 100102;山东中医药大学药学院, 济南, 250014;山东中医药大学药学院, 济南, 250014;山东中医药大学药学院, 济南, 250014 |
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| 基金项目： | 国家自然科学基金课题(30701110) |
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| 摘 要： | 目的]优选苦参的半仿生提取法工艺条件。方法]采用UL(91×33)均匀实验设计,以苦参碱、氧化苦参碱、苦参总碱、高效液相色谱(HPLC)总面积、干浸膏为指标综合评判,优选苦参半仿生提取的工艺条件。结果]3煎用水的pH值依次为2.2008、7.4685、8.9890;3煎总计时间为3.9180h。结论]结合生产实际,确定3煎用水的pH值依次为2.0、7.5、9.0;提取时间依次为2.0、1.0、1.0h。
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| 关 键 词： | 苦参 半仿生提取法 均匀设计 多成分指标 综合评判 |
| 收稿时间： | 2009/9/26 0:00:00 |
Even-designed and optimized technology for semi-bionic extraction of Sophora Flavescens |
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| WANG Ying-zi,HUI Jian-Guo,ZHANG Zhao-wang.Even-designed and optimized technology for semi-bionic extraction of Sophora Flavescens[J].Journal of Tianjin University of Traditonal Chinese Medicine,2010,27(1):66-68. |
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| Authors: | WANG Ying-zi HUI Jian-Guo ZHANG Zhao-wang |
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| Institution: | Beijing University of TCM, Beijing 100102, China;Shandong University of TCM, Jinan 250014, China;Shandong University of TCM, Jinan 250014, China;Shandong University of TCM, Jinan 250014, China |
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| Abstract: | Objective] To optimize the technique of semi-bionic extraction (SBE) for Sophora Flavescens.Methods] Based on the UL (91×33)even-design,matrine,oxymatrine,total alkaloids,total area of HPLC and dry extract were used as indexes to optimize the technology of SBE for Sophora Flavescens.Results] The pH value of 3 times of extraction is 2.2008,7.4685 and 8.9890,respectively.The total extracting time is 3.9180 hours.Conclusion] Based on the manufacture practice,the pH value of extraction of 3 times is 2.0,7.5 and 9.0,respectively and the extracting time is 2 hours,1 hour and 1 hour in turn. |
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| Keywords: | Sophora Flavescens semi-bionic extraction even-design multi-component indexes comprehensive evaluation |
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