速眠新与盐酸氯胺酮对猕猴麻醉效果的初步观察

目的　比较速眠新与盐酸氯胺酮和速眠新复合麻醉对猕猴的麻醉效果。方法　成年健康猕猴 10只 ,动物分成单纯麻醉组 (速眠新组 ,5只 )和复合麻醉组 (速眠新和盐酸氯胺酮组 ,5只 ) ,均采用肌内注射麻醉。结果　速眠新麻醉维持时间仅 0～ 1h ,麻醉效果低于复合麻醉效果。速眠新有较好的镇静、镇痛和肌肉松弛作用 ,复合麻醉使速眠新效果更佳 ,麻醉时间更长、更稳定 (1～ 2h) ,复苏期较快。结论　速眠新和盐酸氯胺酮复合麻醉适合动物实验时间较长的手术 ,是一种较理想的实验动物麻醉方法

The Anesthetic Effect of Sumianxinzhusheye and Ketamine Hydrochloride Injection on Rhesus Monkeys

To explore the genotoxicity effects of passive smoking on Wistar rats, micronuclear test in polychromatic erythrocytes(PCEs) of bone marrow and sperm morphological test on Wistar rats were performed. The sperm malformation rate and the micronuclear rate in passive smoking groups were significantly higher than those in negative controls(P<0.05). The results suggested that the passive smoking not only affects the body cell but also reproductive cells of Wistar rats.