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Attempt at standardization of bone quantitative ultrasound in Japan
Authors:Takahiko Otani  Masao Fukunaga  Kosei Yho  Takami Miki  Kaoru Yamazaki  Hideaki Kishimoto  Mami Matsukawa  Nobuyuki Endoh  Hiroyuki Hachiya  Hiroshi Kanai  Saeko Fujiwara  Yoshinori Nagai
Affiliation:1.Faculty of Science and Engineering,Doshisha University,Kyotanabe,Japan;2.Kawasaki Medical School,Okayama,Japan;3.Aino Hospital,Osaka,Japan;4.Izumiotsu Municipal Hospital,Osaka,Japan;5.Department of Orthopedic Surgery,Iwata City Hospital,Shizuoka,Japan;6.Department of Orthopedic Surgery,Nojima Hospital,Tottori,Japan;7.Department of Electric, Electronics, and Information Engineering, Faculty of Engineering,Kanagawa University,Kanagawa,Japan;8.School of Engineering,Tokyo Institute of Technology,Tokyo,Japan;9.Graduate Schools of Engineering and Biomedical Engineering,Tohoku University,Miyagi,Japan;10.Health Management and Promotion Center,Hiroshima Atomic Bomb Casualty Council,Hiroshima,Japan;11.TM Clinical Support Co. Ltd.,Tokyo,Japan
Abstract:Dual X-ray absorptiometry (DXA) is used to diagnose osteoporosis. On the other hand, quantitative ultrasound (QUS) is widely used to assess bone density as part of medical screening as it is relatively inexpensive and easy to perform. Current QUS devices do not share precise ultrasound-related parameters, such as frequency, waveform, beam pattern, transient response, definition of propagation time, definition of degree of attenuation, and precise measurement site, resulting in different measurements across models. The Japan Osteoporosis Society established a QUS Standardization Committee in 2007 to investigate standardization of speed of sound (SOS) and broadband ultrasonic attenuation (BUA) measurements to resolve this issue. The committee came up with a formula to convert SOS and BUA values yielded by each model available in Japan. This has made it possible to convert QUS measurements from different models into standardized values, greatly improving the effectiveness of QUS measurements.
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