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股骨头缺血坏死中血管内皮生长因子受体的表达
引用本文:王玉峰,梁庆威,王岩峰,范广宇. 股骨头缺血坏死中血管内皮生长因子受体的表达[J]. 中国医科大学学报, 2008, 37(2): 240-241
作者姓名:王玉峰  梁庆威  王岩峰  范广宇
作者单位:中国医科大学,附属第一医院骨科,沈阳,110001
摘    要:目的观察在特发性股骨头缺血坏死(ANFH)中股骨头内血管内皮细胞生长因子受体(flt-1)的表达情况,探讨flt-1在坏死修复中的作用。方法采用免疫组织化学S-P法,检测股骨头内不同部位组织中flt-1的表达水平。结果在坏死区修复端毛细血管内皮细胞flt-1表达阳性。结论flt-1在ANFH的修复过程中起发挥重要作用。

关 键 词:股骨头坏死  内皮生长因子受体
文章编号:0258-4646(2008)02-0240-02
修稿时间:2007-01-17

Research on the Expression of Vascular Endothelial Growth Factor Receptors of the Avascular Necrosis of the Femeral Head
WANG Yu-feng,LIANG Qing-wei,WANG Yan-feng,FAN Guang-yu. Research on the Expression of Vascular Endothelial Growth Factor Receptors of the Avascular Necrosis of the Femeral Head[J]. Journal of China Medical University, 2008, 37(2): 240-241
Authors:WANG Yu-feng  LIANG Qing-wei  WANG Yan-feng  FAN Guang-yu
Abstract:Objective To observe the expressions of flt-1 which are the receptor of vascular endothelial growth factor(VEGF)in the avascular necrosis of the femeral head(ANFH),and to investigate the role of flt-1 during the progress of rehabilitation.Methods We detected the expression of flt-1 in different parts of the femeral heads with the SP immunohistochemistry measurement.Results The positived expression flt-1 could be found in the vascular endthelial cells of the repairing areas.Conclusion Flt-1 plays a significant role during the repair of avascular necrosis of the femeral head(ANFH).
Keywords:necrosis of the femeral head  endothelial growth factor receptors
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