癫痫大鼠海马微血管的扫描电镜观察

应用血管铸型扫描电镜法，对听源性癫痫大鼠海马的微血管进行了观察。结果：癫痫大鼠海马的微血管走行与正常大鼠相似，但其微血管形态与正常大鼠相比有明显差异。癫痫大鼠海马微动脉的内皮细胞核压迹分布无一定规律，微动脉内表面凹凸不平。癫痫大鼠海马的小管微动脉环平行平滑压肌压迹急剧增多。

A SCANNING ELECTRON MICROSCOPIC STUDY ON HIPPOCAMPAL MICROVESSEL IN EPILEPSIA RAT

The hippocampal microvessels in the rat with audiogenic seizure were studied by scanning electron microscopy on corrosion casts. The results showed that the hippocampal vasculature in the epilepsia rat was similar to that of normal rats. Compared with the normal rat. there was significant difference in the morphology of the hippocampal microvessels in the epilepsia rat. The nuclear impression of endothelial cells on the hippocampal arteriole in the epilepsia rat was irregular. and the interior surface of the arteriole was uneven. The impression of smooth muclear cells on minor arterioles increased greatly. Arteriole-arteriole anastomosis . artcriole-venule anastomosis . capillary-capillary anastomosis were common anastomotic types between hippocampal microvessels in the epilepsia rat. The type and the number of the special hippocampal microvessels in the epilepsia rat were more than that in the normal rat. The results suggested that the morphological changes of hippocampal microvessels in the epilepsia rat might be associated with audiogenic seizure.