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Repeat medication errors in nursing homes: Contributing factors and their association with patient harm
Authors:Daniel J Crespin  Anuja V Modi  David Wei  Charlotte E Williams  Sandra B Greene  Stephanie Pierson  Richard A Hansen
Institution:1. Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;2. Welsh School of Pharmacy, Cardiff University, Cardiff, Wales, United Kingdom;3. Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;4. Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;1. Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, 3052, Australia;2. NHMRC Cognitive Decline Partnership Centre, Level 3, Old Leighton Lodge (Building 8 via Gate 6), Department of Rehabilitation and Aged care (RACS), Hornsby Ku-ring-gai Hospital, Palmerston Road, Hornsby, New South Wales, 2077, Australia;3. School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, 3004, Australia;4. Brightwater Research Centre, Brightwater Care Group, Level 3, 355 Scarborough Beach Rd, Osborne Park, Western Australia, 6017, Australia;5. Helping Hand, 34 Molesworth St, North Adelaide, South Australia, 5006, Australia;6. Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, South Australia, 5001, Australia;1. MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, 200 Renfield Street, Glasgow G2 2QB, United Kingdom;2. Dept. of Social Policy, London School of Economics, Houghton Street, London, WC2A 2AE, United Kingdom;3. Centre for Public Health, Institute of Clinical Sciences, Royal Hospitals Site, BT12 6BJ, Queen’s University Belfast, Belfast, United Kingdom;1. Department of Trauma and Orthopaedic Surgery, Aintree University Hospital NHS Foundation Trust, Liverpool, England;2. Department of Trauma and Orthopaedic Surgery, Royal Liverpool and Broadgreen University Teaching Hospitals, Liverpool, England;3. Department of Trauma and Orthopaedic Surgery, Royal National Orthopaedic Hospital NHS Trust, Brockley Hill, England;4. School of Health Care Professions, University of Salford, Salford, England;5. Lam Wah Ee Hospital, Penang, Singapore
Abstract:Background: Medication errors are highly prevalent in long-term care facilities and are responsible for preventable injury. Repeat medication errors, or identical events occurring multiple times in the same patient, may be particularly preventable.Objectives: This study assessed the factors that contribute to repeat medication errors and the association between repeat medication errors and patient harm.Methods: In this cross-sectional analysis, medication error reports submitted by licensed nursing homes to North Carolina's Medication Error Quality Initiative-Individual Error Web-based incident reporting system were analyzed for fiscal years 2006–2008. When reporting errors, the sites were asked whether the event was identically repeated within the same patient. Repeat medication errors were defined as identical events in terms of patient characteristics, drug involved, error type, potential cause, phase of the medication care process, and personnel involved. Repeat errors were compared with nonrepeat errors. Multivariate logistic regression was used to explore whether certain patient or error characteristics were related to a higher likelihood of repeat errors, and a similar analysis was used to explore whether repeat errors were related to patient harm.Results: Of the total 15,037 errors reported by 294 unique nursing homes, 5615 (37.3%) were repeated one or more times. Among the repeat errors, the associated event within each error was repeated a mean (SD) of 10.7 (14.3) times. Wrong dosage (65.1% 3654/5615]) and wrong administration (10.2% 571/5615]) were the most frequent repeated events. In multivariate analysis, repeat errors occurred less frequently among younger residents (aged <75 years) than among older residents (aged ≥75 years) (odds ratio OR] = 0.85; 95% CI, 0.79–0.93) and among residents able to direct their own care compared with cognitively impaired residents (OR = 0.87; 95% CI, 0.81–0.95). Patient harm was reported in only 1.2% (68/5615) of repeat errors and 0.6% (55/9422) of non-repeat errors. A multivariate analysis of patient harm found that repeat errors were more likely to be harmful than were nonrepeat errors (OR = 2.11; 95% CI, 1.43–3.11).Conclusions: Repeat medication errors in nursing homes are a common occurrence and have greater odds of being associated with harm than do nonrepeat errors. Future patient-safety research should focus on factors related to repeat errors.
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