基于3469例血管病变患者证候分布规律的脉络病变共性病机探讨

目的 探讨脉络病变共性病机.方法 选择3469例血管病变患者开展临床流行病学调查,以熵的复杂系统分划方法提取证候,计算构成比,建立结构方程模型研究证候间因果关系.结果 3469例患者分为8个共性证候,络气郁滞证占31.94%,络气虚滞证占58.58%,兼有络气郁滞和虚滞证者占9.48%;血瘀58.11%、痰浊(热)42.66%、郁热24.59%、阴虚29.14%、阳虚28.37%;络气郁滞、络气虚滞均能引起血瘀、痰浊,络气郁滞可引起郁热.结论 络气郁滞与络气虚滞为脉络病变始动因素并贯穿全过程,痰、瘀、热既是病理产物又是继发性致病因素.

Research on Common Pathogenesis of Vessel Diseases of 3469 Patients based on TCM Syndrome Distribution

Objective To study the common pathogenesis of the vessel diseases.Methods The epidemiological study was carried out on 3469 patients with vascular diseases,the TCM syndromes were diagnosed by using the entropy-based complex system partition method,the syndrome constituent ratio was calculated,and the structural equation model was set up for studying the causality among the syndromes.Resnlts There were 8 common syndromes in 3469 patients.Collateral-qi stagnation syndrome was 31.94%.Collateral-qi deficiency syndrome was 58.58%.Collateral-qi stagnation combined with collateral-qi deficiency syndrome was 9.48%.Blood stasis syndrome was 58.11%.Phlegm turbidity(fire)syndrome was 42.66%.Stagnation heat syndrome was 24.59%.Yin deficiency syndrome was 29.14%.Yang deficiency syndrome was 28.37%.Both collateral-qi stagnation and collateral-qi deficiency could induce blood stasis and phlegm turbidity while collateral-qi stagnation could also cause stagnation heat.Conclusion Collateral-qi stagnation and collateral-qi deficiency were the initiating agent,which existing in the whole process of vessel disease.Blood stasis,phlegm and stagnation heat were the pathological products and secondary causative factors as well.