浙江省1996～2007年妊娠合并重型肝炎孕产妇死亡情况分析

目的:总结分析妊娠合并重型肝炎孕产妇死亡病例的特点及经验教训,减少疾病发生率,提高救治成功率。方法:对浙江省1996～2007年间共51例妊娠合并重型肝炎孕产妇死亡病例进行回顾性分析。结果:51例死亡病例中,44例为农村人口,7例为城市人口;流动人口6例,均发生在后6年。大多数患者在孕晚期发病,主要以消化道症状、皮肤黄染或目黄尿黄等症状起病。共有44例患者进行了不同次数的转诊,将第1次转诊与第2次及以上转诊的有意义转诊率进行比较,两者有显著性差异。结论:妊娠合并重型肝炎孕产妇死亡人群主要为经济条件相对较差的农村人口及流动人口,要加大对农村地区的资源投入、加强社会宣传教育、完善流动人口管理,要早预防、早发现,一旦发病及时转诊至有条件的医院救治。

Analysis on death status of severe hepatitis during pregnancy in Zhejiang province from 1996 to 2007

Objective:To summarize and analyze the characteristics and experiences of deaths of severe hepatitis during pregnancy,decrease the incidence and increase the success rate of therapy.Methods:Clinical data of 51 deaths of severe hepatitis during pregnancy from 1996 to 2007 were analyzed retrospectively in Zhejiang province.Results:Among 51 deaths,44 deaths were from rural areas,while 7 deaths were from urban areas.Six deaths were floating population,and all of them took place in the latter 6 years.Most of the deaths became ill on third trimester with the initial symptoms of gastrointestinal unfitness and jaundice.44 cases were transported to other hospitals for once or many times,and there was significant difference in reliable transportation rate between the first transportation and the second transportation.Conclusion:The deaths caused by severe hepatitis during pregnancy are mainly from poor conditioned rural areas and floating population.More health care resources in rural areas,better health care education,more effective administration of floating population and strategies such as early prevention,early diagnosis,and early transportation to qualified hospitals should be considered.