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载脂蛋白与Ⅱ型糖尿病及其并发症的关系
引用本文:范志广,王纯红,朱俊英.载脂蛋白与Ⅱ型糖尿病及其并发症的关系[J].黑龙江医学,2006,30(12):896-897.
作者姓名:范志广  王纯红  朱俊英
作者单位:黑龙江省医院南岗分院,黑龙江,哈尔滨,150001;黑龙江省医院南岗分院,黑龙江,哈尔滨,150001;黑龙江省医院南岗分院,黑龙江,哈尔滨,150001
摘    要:目的观察载脂蛋白与Ⅱ型糖尿病(T2DM)及其并发症的关系。方法载脂蛋白APOA1、APOB采用免疫透射比浊法测定;TC、TG、HDL-C采用酶法测定。试剂为上海科华公司。仪器为美国贝克曼CX7全自动生化分析仪。结果T2DM合并冠心病组、肾病组的APOB分别高于正常人、视网膜微血管病组、无血管并发症组。T2DM各组的APOA1/B比值均高于正常人,且合并冠心病组、肾病组,分别高于视网膜微血管病组与无血管并发症组。结论APOA1、APOB与T2DM动脉硬化关系密切,APOA1/B比值是反映T2DM脂代谢的敏感指标。

关 键 词:Ⅱ型糖尿病  载脂蛋白APOA1、APOB
文章编号:1004-5775(2006)12-0896-02
收稿时间:10 10 2006 12:00AM
修稿时间:2006年10月10

Relationship between APO and Type 2 Diabetes
FAN Zhi-guang,WANG Chun-hong,ZHU Jun-ying.Relationship between APO and Type 2 Diabetes[J].Heilongjiang Medical Journal,2006,30(12):896-897.
Authors:FAN Zhi-guang  WANG Chun-hong  ZHU Jun-ying
Institution:The Nangang Branch of Heilongjiang Provincial Hospital, Harbin 150001, China
Abstract:Objective To observe the relationship between APO and type 2 diabetes and its complication. Methods The APO was detected with immuno- turbidimetry, and TC, TG, HDL were detected with enzyme method. The kit was from shanghai with American Beckmen CX7 analyzer. Results The APOB of type 2 diabetes with coronary heart disease and renal disease was higher than that in nomud, retinal and non - blood vessel involved group as well as APOA1/B. Conclusion There was close relationship between APOA1, APOB and arteriosclerosis of type 2 diabetes, and if reflect the lipid metabolism sensitive data.
Keywords:Type II diabetes  APOA1  APOB
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