XE-5000研究参数白细胞分类结果与镜检对比

目的 探讨XE-5000全自动血细胞分析仪白细胞不能分类时研究参数中白细胞分类计数的准确性.方法 选择XE-5000白细胞不能分类的血液病患者66例和非血液病患者66例,分别进行涂片染色显微镜镜检分类.对XE-5000研究参数中白细胞分类结果与镜检结果进行相关性分析,比较两者结果的关系.结果 血液病组中性粒细胞、淋巴细胞、单核细胞、嗜酸性粒细胞和嗜碱性粒细胞相关系数分别为0.933、0.959、0.654、0.846和0.417(P<0.01).非血液病组中性粒细胞、淋巴细胞、单核细胞、嗜酸性粒细胞和嗜碱性粒细胞相关系数分别为0.882、0.908、0.416、0.420(P<0.01)和0.069(P>0.05).两种方法相比较,中性粒细胞、淋巴细胞呈高度正相关,单核细胞、嗜酸性粒细胞呈中度正相关.结论 XE-5000全自动血细胞分析仪研究参数中白细胞分类结果可靠,具有准确、简便、快速等优点,为分类提供一个可行方法,临床可参考研究参数分类结果出报告.

Comparison of the differential counts of white blood cells detected by XE-5000 and microscopic examination

Objective To investigate the accuracy of differential counts of white blood cells(WBC) detected by XE-5000, when WBC parameters could not be classified.Methods 66 cases of blood samples collected from patients with hematopathy(hematophathy group) and 66 cases of blood samples collected from patients without hematopathy(non-hematopathy group), in which WBC could not be classified by XE-5000 were detected by microscopic examination for the differential counts of WBC, and the differential counts detected by the two methods were analyzed for the correlation between them.Results In hematophathy group, the coefficient correlation of neutrophils, lymphocytes, monocytes, eosinophils and basophils were 0.933,0.959,0.654,0.846 and 0.417(P<0.01), and in non-hematopathy group were 0.882,0.908,0.416, 0.420 (P <0.01) and 0.069 (P>0.05) respectively. Comparison between the results of the two methods indicated that there was fine positive correlation of neutrophils and lymphocytes, and moderate positive correlation of monocytes and eosinophils.Conclusion Differential counts of WBC, detected by XE-5000 automated hematology analyzer, were reliable and accurate, with the advantages of convenience and rapidity, could be a feasible method, and detected results of differential counts of WBC could provide reference for clinical reports.