| 孕妇ABO血型抗A(B)抗体效价检测分析 |
| |
| 引用本文： | 孙小纯,欧兴义,林伟强,陈亚军,陈晖,石晶.孕妇ABO血型抗A(B)抗体效价检测分析[J].国际检验医学杂志,2012,33(6):719+721. |
| |
| 作者姓名： | 孙小纯 欧兴义 林伟强 陈亚军 陈晖 石晶 |
| |
| 作者单位： | 广东省珠海市人民医院,519000 |
| |
| 摘 要： | 目的 了解该地区孕妇ABO血型抗A(B)IgG抗体效价异常率,分析其在新生儿溶血病(HDN)中的意义.方法 采用微柱凝胶法对4 000例孕周20周以上、O型血孕妇(丈夫为非O型血)进行血清抗A(B)IgG抗体效价检测;对抗体效价大于1∶64者所分娩新生儿进行HDN试验检测,分析抗体效价与HDN发病率的关系.结果 4 000例孕妇中,血清抗A(B)IgG抗体效价大于1∶64者有432例,异常率为10.8%(432/4 000);295例血清抗A(B)IgG抗体效价大于1∶64者所分娩的新生儿中,HDN发病率为53.9%(159/295).结论 随着血清IgG抗A(B)效价增高,HDN发病率也增高;产前抗体效价检测是可用于判断HDN发病风险的筛查指标.
|
| 关 键 词： | 溶血 ABO血型系统 母婴血型不合 婴儿 新生 |
Titer analysis of ABO blood type anti-A(B) antibody in gravida |
| |
| Sun Xiaochun
,
Ou Xingyi
,
Lin Weiqiang
,
Chen Yajun
,
Chen Hui
,
Shi Jing.Titer analysis of ABO blood type anti-A(B) antibody in gravida[J].International Journal of Laboratory Medicine,2012,33(6):719+721. |
| |
| Authors: | Sun Xiaochun Ou Xingyi Lin Weiqiang Chen Yajun Chen Hui Shi Jing |
| |
| Institution: | (People’s Hospital of Zhuhai City,Zhuhai Guangdong 519000,China) |
| |
| Abstract: | Objective To analyze the abnormal rate of ABO blood group anti-A(B) IgG antibody titer in gravida in this area and its relationship with hemolytic disease of the newborn(HDN).Methods Microcolumn gel method was performed for the detection of antibody titer in 4 000 cases of gravidas.Neonatus,delivered by gravida with antibody titer more than 1:64,were detected with HDN tests.Relationship between antibody titer and the incidence rate of HDN was analyzed.Results The abnormal rate of antibody titer was 10.8%(432/4 000).In neonatus,delivered by gravida with abnormal antibody titer,the incidence rate of HDN was 53.9%(159/295).Conclusion The incidence rate of HND could increase with the increasing of the titer of anti-A(B) antibody in gravida.Detection of antibody titer before delivery might be an effective indicator for the screening of HDN. |
| |
| Keywords: | hemolysis ABO blood group system maternal-fetal blood group incompatibility infant newborn |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
