某地区吸毒者HIV感染状况调查及细胞免疫功能分析

目的 了解该地区吸毒者人类免疫缺陷病毒(HIV)感染状况及免疫功能.方法 对4 827例吸毒者进行调查,及HIV抗体和T淋巴细胞亚群检测.结果 HIV抗体阳性率为1.28%(62/4 827),大部分HIV感染者非该地区祖籍者[75.81%(47/62)]、采用静脉注射式吸毒[80.65%(50/62)]、吸毒史为(>5~10)年[67.74%(42/62)]、年龄范围为(19~＜35)岁[69.35%(43/62)].HIV阳性者CD3+CD4+T淋巴细胞数及CD4+/CD8+比值均低于健康者(P<0.05).结论 该地区HIV感染吸毒者存在低龄化和地域外来化趋势,需加强相关管理措施,重视健康教育.

HIV prevalence and cellular immune function analysis among drug addicts in certain area

Objective To investigate the prevalence of human immunodeficiency virus(HIV) and immune function among drug addicts in this area.Methods 4 827 cases of drug addicts were surveyed,and detected for anti-HIV antibody and subgroups of T lymphocyte.Results The positive rate of anti-HIV antibody was 1.28%(62/4 827).Most HIV-positive drug addicts were from other regions[75.81%(47/62)],injection drug users[80.65%(50/62)],with a history of drug abuse for more than three to five years and at the age of nineteen to less than thirty-five years old.The amount of CD3+CD4+T lymphocyte and ratio of CD4+/CD8+ were both lower than healthy subjects(P<0.05).Conclusion There could be a trend of foreign districts and younger age among HIV-positive drug addicts in this area,and management measures and of health education should be strengthened.