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147株金黄色葡萄球菌耐药现状分析
引用本文:韩飞,李建英,牟君成,周政. 147株金黄色葡萄球菌耐药现状分析[J]. 国际检验医学杂志, 2012, 33(6): 720-721
作者姓名:韩飞  李建英  牟君成  周政
作者单位:重庆三峡中心医院微免科,404000
摘    要:目的 研究金黄色葡萄球菌(SAU)临床分离株的耐药性,为合理使用抗菌药物提供依据.方法 采用VITEK 2 Compact型全自动微生物分析系统进行菌株鉴定和药敏试验,统计分析147株SAU的标本分布及耐药率.结果 分泌物标本SAU检出率最高;耐甲氧西林金黄色葡萄球菌(MRSA)分离率达40.1%(59/147).SAU对多种抗菌药物具有不同程度的耐药性,对呋喃妥因、利奈唑胺、奎努普汀/达福普汀、替加环素、万古霉素敏感率为100.0%.结论 SAU临床分离株耐药现状严重,MRSA的耐药情况更为严重,临床微生物实验室应加强MRSA监测工作.

关 键 词:金黄色葡萄球菌  耐甲氧西林金黄色葡萄球菌  耐药性

Drug-resistance analysis of 147 strains of Staphylococcus aureus
Han Fei , Li Jianying , Mu Juncheng , Zhou Zheng. Drug-resistance analysis of 147 strains of Staphylococcus aureus[J]. International Journal of Laboratory Medicine, 2012, 33(6): 720-721
Authors:Han Fei    Li Jianying    Mu Juncheng    Zhou Zheng
Affiliation:(Department of Microbiology and Immunology,Chongqing Three Gorges Central Hospital,Chongqing 404000,China)
Abstract:Objective To analyze the drug-resistance of Staphylococcus aureus(SAU) isolated from clinical samples,and provide scientific evidence for reasonable usage of antibiotics.Methods Clinical distribution and drug-resistance for 147 strains of SAU were analyzed by VITEK 2 Compact analyzer.Results Mainly of the 147 strains of SAU were isolated from secretion specimens.The isolating of methicillin resistant Staphylococcus aureus(MRSA) was 40.1 %(59/147).Clinical isolates of SAU were resistant to antibiotics at different degree,with sensitivity rate of 100.0% to Nitrofurantoin,Linezolid,Quinupristin/Dalfopristin,Tigecycline and Vancomycin.Conclusion Drug-resistance status of SAU,especially MRSA,might be severe,and the monitoring of MRSA should be further strengthened in clinical microbiology laboratory.
Keywords:Staphylococcus aureus  methicillin-resistant Staphylococcus aureus  drug resistance
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