XD-684型电解质分析仪在血锂测定中的应用

目的评价XD-684型电解质分析仪检测血锂浓度的可信度与实用性。方法对36例服用碳酸锂治疗的情感性精神障碍患者分别于治疗第1、3、5周末采用XD-684型电解质分析仪检测其血锂浓度,观察碳酸锂服药剂量与血锂浓度的关系;用3种不同锂离子浓度的质控液随每批标本检测,衡量该仪器检测结果的准确性和精密性。结果该仪器变异系数均在其允许范围内(≤3.0%),说明检测结果准确性高、重复性好,口服碳酸锂剂量与检测血锂浓度呈显著正相关(r=0.928,P<0.01)。结论该仪器检测血锂浓度快速、准确,建议临床实验室推广使用。

Application of the XD-684 clinical electrolyte analyzer in testing the serum lithium concentrations

Objective To appraise the reliability and the practicability of the XD-684 clinical electrolyte analyzer in testing lithium in serum. Methods 36 patients with affective disorder were treated with lithium carbonate. Ser um lithium concentrations were tested using the XD-684 clinical electrolyte analyzer at the end of the 1st, 3rd and 5th week. The relationships between the dosage of lithium carbonate and the concentrations of lithium in serum were ob- served. Three kinds of quality control solution were detected with different concentrations of lithium when each batch of sample was measured to evaluate accuracy and precision of the equipment. Results The results of equipment were accurate and had better reproducibility. The dose of orally lithium carbonate had positive correlation with lithium in serum（r=0. 928 ,P〈0.01）. Conclusion This equipment can analyze the concentrations of serum lithium quickly,accurately and safely. It should be used widely in clinical laboratory.