251例结肠息肉切除术后再发危险因素分析

目的 探讨结肠息肉切除术后再发的危险因素。方法 回顾性分析251例结肠息肉切除术后患者再发的危险因素。结果 男性、结肠息肉部位多发于全结肠、息肉个数>10个均为结肠息肉再发的危险因素（P值分别为0.009、<0.001、0.028）。再发组（160例）癌胚抗原水平高于未再发组（P=0.014），而年龄、同型半胱氨酸水平...

Analysis of risk factors of postoperative colorectal polyps recurrence in 251 patients

Objective To evaluate the significance of risk factors of colorectal polyps recurrence after polypectomy. Method The risk factors of colorectal polyps recurrence after polypectomy in 251 patients were retrospectively analyzed. Results Male, multiple location of colonic polyps （the whole colon） and number of polyps （> 10）were the risk factors for the recurrence of colonic polyps （P = 0.009, < 0.001 and 0.028）. Carcinoembryonic antigen （CEA） level was higher in the recurrence group than the non-recurrence group（P = 0.014）. Age, homocysteine level and number of patients with hypertension in the recurrence group（n = 160） were also higher compared with those in the non-recurrence group（n = 91）, while no statistical significance was observed （P = 0.076, 0.077 and 0.077）. The risk of hyperplastic polyps recurrence was significantly lower （P = 0.023）. No other metabolic factors, such as obesity, diabetes mellitus, fatty liver, triglyceride, LDL, uric acid and colorectal polyps were found to be associated with the recurrence of colonic polyps （P = 0.444, 0.641, 0.541, 0.889, 0.362, 0.247 and 0.248）. Multivariate logistic regression analysis further showed that male and polyps located in the ascending colon were intimately correlated with colorectal polyps recurrence （P = 0.033 and 0.003）.Conclusions Male, multiple location of colonic polyp （the whole colon） and number of polyps （> 10） are risk factors of colorectal polyps recurrence. The risk of hyperplastic polyps recurrence is relatively low. CEA level is positively associated with colorectal polyps recurrence. Male and multiple location of colonic polyp （the whole colon） are significantly associated with colorectal polyps recurrence.