SARS-CoV-2 IgG Amongst Dental Workers During the COVID-19 Pandemic |
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Authors: | Irena Duś-Ilnicka Anna Szczygielska Amadeusz Kuźniarski Aleksander Szymczak Lilla Pawlik-Sobecka Małgorzata Radwan-Oczko |
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Institution: | 1. Department of Oral Pathology, Wroclaw Medical University, Wroc?aw, Poland;2. Department of Prosthetic Dentistry, Wroclaw Medical University, Wroc?aw, Poland;3. Bacteriophage Laboratory Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroc?aw, Poland;4. Department of Nervous System Diseases, Wroclaw Medical University, Wroc?aw, Poland |
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Abstract: | ObjectivesSince the SARS-CoV-2 outbreak in 2019, special safety protocols have been introduced in dentistry. Dental professionals were determined to be mostly at risk for contracting the virus due to aerosol-generating procedures used. This preliminary study starts the cycle of the laboratory protocols describing the quality and efficacy of laboratory tests in the SARS-CoV-2 immunoglobulin G (IgG) detection in the serum of asymptomatic dental personnel during the last quarter of 2020.MethodsIgG levels were measured with the use of a semi-quantitative enzyme-linked immunosorbent assay (ELISA) in vitro diagnostic kit in the serum of a study group that consisted of 127 employees of the dental clinic divided into 3 subgroups: SUB1: dentists (n = 67); SUB2: dental assistants, dental hygienists, nurses, laboratory workers (n = 40); SUB3: administrative workers (n = 20). Pearson analysis of results from the questionnaires attached to the study protocol were provided to assure that the results compare to the participants’ impressions about their general health.ResultsPositive ELISA IgG results were found in 6% (n = 4) of the SUB1 group, 7.50% (n =3) of the SUB2 group, and 5% of the SUB3 group. The percentage of participants without work interruption from the beginning of the pandemic was 54% of dentists and 60% of chairside assistants.ConclusionsSerum IgG prevalence with the use of a semi-quantitative test was low, and further research on the biobanked samples should follow to determine the levels of IgG with quantitative methods and/or to evaluate the presence of neutralising antibodies in dental personnel. Because of the low representation of seropositivity studies in this group, it will be crucial to confirm the risk of COVID-19 transmission in dental offices. |
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Keywords: | COVID-19 SARS-CoV-2 Dentists Aerosol Immunoglobulin G |
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