腹腔镜保留肾单位手术围术期预防性使用抗凝药物的安全性

目的 分析腹腔镜保留肾单位手术患者在围术期预防性使用抗凝药物的安全性。方法 回顾性分析接受腹腔镜保留肾单位手术的84例患者资料，包括其基线资料及术中出血量、术中输血率、术后再次出血发生率、术后血红蛋白下降值及术后住院时间等。比较围术期预防性使用抗凝药物患者（药物组，50例）与未使用抗凝药物患者（非药物组，34例）的上述...

Safety of perioperative prophylactic anticoagulation in laparoscopic nephron-sparing surgery

Objective To analyze the safety of perioperative prophylactic anticoagulant therapy in patients undergoing laparoscopic nephron-sparing surgery. Methods Clinical data of 84 cases underwent laparoscopic nephron-sparing surgery were retrospectively analyzed. The baseline data, intraoperative blood loss, intraoperative blood transfusion rate, postoperative rebleeding rate, postoperative hemoglobin reduction value, and postoperative length of hospital stay were recorded. These parameters were statistically compared between patients treated with perioperative prophylactic anticoagulant therapy （medicine group, n = 50） and without perioperative prophylactic anticoagulant therapy （non-medicine group, n = 34）. Results There was no significant difference in intraoperative blood loss （50.0 （30.0,100.0）mL vs.50.0 （45.0,100.0）mL）, intraoperative blood transfusion rate （0 vs.2.9%）, postoperative rebleeding rate （4.0% vs.2.9%）, postoperative hemoglobin reduction value （14.0（8.0,23.0） g/L vs.17.7（9.3,28.5） g/L）, and postoperative length of hospital stay （6.0（5.0,7.0）d vs.7.0（4.0,9.3）d）between the medicine and non-medicine groups （all P > 0.05）. Conclusion Perioperative prophylactic anticoagulation is safe and feasible for patients undergoing laparoscopic nephron-sparing surgery.