| 远红外线治疗妇科癌症术后下肢淋巴水肿的安全性研究 |
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| 引用本文： | 王小点,崔春晓,夏亮,冯少清,喜雯婧,肖文天,孟心娴,韩承尧,李科,章一新. 远红外线治疗妇科癌症术后下肢淋巴水肿的安全性研究[J]. 组织工程与重建外科, 2022, 0(1): 19-24 |
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| 作者姓名： | 王小点 崔春晓 夏亮 冯少清 喜雯婧 肖文天 孟心娴 韩承尧 李科 章一新 |
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| 作者单位： | 上海交通大学医学院附属第九人民医院整复外科;复旦大学眼耳鼻喉科医院眼耳鼻整形外科;上海交通大学医学院附属第九人民医院口腔颅颌面外科 |
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| 基金项目： | 国家自然科学基金项目(82000456)。 |
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| 摘 要： | 目的 探讨远红外线治疗妇科癌症术后淋巴水肿患者的有效性和安全性.方法 2013年1月至2020年1月,选取74名妇科癌症术后淋巴水肿的患者,分别接受绷带治疗(n=35)和远红外线+绷带治疗(n=39).1年后评估患者淋巴水肿肢体积液量、淋巴水肿肢体周径、血清肿瘤标志物CA125;记录阴道、腹股沟-盆腔淋巴结变化情况,以...
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| 关 键 词： | 淋巴水肿 妇科癌症术后淋巴水肿 远红外线 绷带治疗 |
Efficacy and safety of far infrared radiation in the treatment of gynecological cancer-related lymphedema |
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| WANG Xiaodian,CUI Chunxiao,XIA Liang,FENG Shaoqing,XI Wenjing,XIAO Wentian,MENG Xinxian,HAN Chenyao,LI Ke,ZHANG Yixin. Efficacy and safety of far infrared radiation in the treatment of gynecological cancer-related lymphedema[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2022, 0(1): 19-24 |
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| Authors: | WANG Xiaodian CUI Chunxiao XIA Liang FENG Shaoqing XI Wenjing XIAO Wentian MENG Xinxian HAN Chenyao LI Ke ZHANG Yixin |
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| Affiliation: | (Department of Plastic and Reconstructive Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China;Department of Facial Plastic and Reconstructive Surgery,ENT Institute,Eye and ENT Hospital,Shanghai Fudan University,Shanghai 200433,China;Department of Oral and Cranio-Maxillofacial Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China) |
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| Abstract: | Objective To investigate the efficacy and safety of far infrared radiation(FIR)in treating gynecological cancer-related lymphedema.Methods From January 2013 to January 2020,74 patients with gynecological cancer-related lymphedema were randomly allocated into two treatment groups:group of bandage treatment(n=35)and group of FIR plus bandage treatment(n=39).Variations of fluid,circumference of lymphedematous limbs,serum tumor markers CA125,inguinal-pelvic lymph nodes,vagina,lungs,and adverse reactions were assessed 1 year after treatment.In vitro experiment was used to examine the effects on cell viability,proliferation,apoptosis,and cell cycle of fibroblasts,A2780,HeLa,Ishikawa and SKOV-3 cells.Results The FIR+bandage group showed significantly decreased tissue fluid and reduced limb circumference(P<0.05)in comparison with the bandage group at 1 year of follow-up.There was no increase of serum CA125 in both groups,and no recurrence of neoplasia or lymphadenopathy was detected.No adverse reactions were recorded.In addition,no changes were detected after FIR treatment for fibroblasts,A2780,HeLa,Ishikawa and SKOV-3 cells in cell viability,proliferation,apoptosis,and cell cycle.Conclusion The combination of FIR and bandage therapy is more effective in the treatment of gynecological cancer-related lymphedema,and does not promote the recurrence or metastasis of gynecological cancer,and is well tolerated without adverse reactions or side effects. |
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| Keywords: | Lymphedema Gynecological cancer-related lymphedema Far infrared radiation Bandage therapy |
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