口腔黏膜疾病临床病理诊断统计分析

目的：分析进行活体组织检查病理诊断的口腔黏膜病变的病理资料及其与患者基本信息、临床基本病损及临床诊断等的相关性,为口腔黏膜病的临床诊断提供参考。方法：收集2003年1月至2007年3月在广西医科大学附属口腔医院就诊,诊断为口腔黏膜疾病并取活体组织检查病例353例,对其临床病损、病理诊断及临床病理诊断符合率的相关性进行系统分析。结果：在353例黏膜病中,男151例,女202例。主要好发于颊、舌、唇等处黏膜,病程多数不超过1年。其中289例口腔黏膜病病理确诊,病理确诊率81.87%。此外有64例口腔黏膜疾病在组织病理学上无法确诊,与多种口腔黏膜疾病表现相似,不能完全排除其他疾病的诊断。在289例病理确诊的资料中以口腔黏膜斑纹类疾病为主174例（60.21%）,其中扁平苔藓76例（26.3%）,白斑60例（20.76%）,慢性盘状红斑狼疮38例（13.15%）。其次为溃疡类疾病49例（16.96%）,其他疾病66例（22.83%）等。发现12例在组织病理学上确诊的黏膜良性淋巴组织增生病。结论：口腔黏膜疾病病种繁多,临床表征类似,病理诊断是临床确诊与治疗的重要依据。

STUDY ON THE CLINICAL AND PATHOLOGICAL DIAGNOSIS IN PATIENTS WITH ORAL MUCOSAL DISEASES

Objective：The objective of this study was to analyze the correlation of pathological document of oral mucosal lesions by biopsy with the general information of patients and clinical lesions for the clinical diagnosis. Methods：Three hundred and fifty-three biopsied patients with oral mucous diseases from Stomatology Hospital of Guangxi Medical University were included in this investigation. Clinical and pathological diagnoses were analyzed for the accordance rate. Results. Three hundred and fifty-three biopsied patients were made of 151 males and 202 females. The lesions mainly occurred in cheeks, tongues, lips etc. The duration of most patients was less than one year. Two hundred and eighty-nine cases （81.87%） with oral mucosal diseases had been pathologically diagnosed. In addition, due to the resemble manifestions of several oral mucosal diseases, 64 cases could not be diagnosed according to pathology. Among the 289 diseases, 174 species manifested as patch like lesions in clinical appearance （60. 21 %）, including 76 （26.3 %）cases diagnosed as oral lichen planus pathologically,60（20.76%）cases as oral leukoplakia,38（13.15%）chronic discoid lupus erythematosus, oral ulcer 49（16.96%）, the others 66（22.83%）, etc. Meanwhile, 12 cases were diagnosed as benign lymphadenosis of mucosa which was known for lymphadenosis. Conclusion. The clinical appearances of oral mucous diseases are similar, biopsy and pathological diagnosis play an important role in the clinical diagnosis and treatment of the oral mucosal diseases.