抑郁症病人与正常人骨矿物质密度的对照研究

目的 研究抑郁症病人是否存在骨矿物密度的异常并探讨其机理。方法 用单光子骨矿物质密度测定仪测查３４例抑郁症病人尺，桡骨下１／３处骨矿物质密度并与正常人进行对照，要抑郁症病人尺，桡骨骨矿物质密度均较同性别的正常对照显著下降。结论 抑郁症是骨质疏松症是一个重要危险因素，可能与抑郁症病人伴有的神经内分泌及免疫功能改变有关。

A controlled study on bone mineral density between patients with major depression and healthy subjects

Objective To study whether the bone mineral density in depression is abnormal and explore the mechanisms.Methods The bone mineral density of lower one third part of ulna and radius in 34 depressive patients was measured by single photo bone mineral density measure instrument and compare it with which of healthy subjects.Results The bone mineral density of ulna and radius in depressive patients were lower than healthy subjects of the same sex and the differences were signifcant.Conclusions Major depression is an important risk factor for osteoporosis,which may be result of the alteratons of neuroendocrine and immune functions in depressive patients.