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Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder |
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| Authors: | Adele F Dimian Kelly N Botteron Stephen R Dager Jed T Elison Annette M Estes Jr" target="_blank">John R PruettJr Robert T Schultz Lonnie Zwaigenbaum Joseph Piven Jason J Wolff The IBIS Network |
| Institution: | 1.Department of Educational Psychology,University of Minnesota,Minneapolis,USA;2.Department of Psychiatry,Washington University in St. Louis,St. Louis,USA;3.Department of Radiology,University of Washington,Seattle,USA;4.Institute of Child Development,University of Minnesota,Minneapolis,USA;5.Department of Speech and Hearing Sciences,University of Washington,Seattle,USA;6.Center for Autism Research,Children’s Hospital of Philadelphia,Philadelphia,USA;7.Department of Pediatrics,University of Alberta,Edmonton,Canada;8.Department of Psychiatry,University of North Carolina at Chapel Hill,Chapel Hill,USA |
| Abstract: | Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose of this study was to evaluate behavioral characteristics predicting SIB at age 2 years among 235 infants at high familial risk for ASD. Logistic regression results indicated that presence of SIB or proto-SIB and lower developmental functioning at age 12 months significantly predicted SIB at 24 months. A pattern of persistent SIB over this period was associated with a diagnosis of autism and poorer cognitive and adaptive outcomes. |
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