注射感染马来丝虫微丝蚴在蚊虫体内早期发育的观察

本文报告经注射感染的马来丝虫微丝蚴在幼龄中华按蚊、幼龄致倦库蚊和老龄致倦库蚊体内早期发育变化的情况。接种后60h,幼丝虫在这三类蚊虫体内的发育已有明显差异。幼龄中华按蚊体内正常发育的幼丝虫比例最高(72.3％);幼龄致倦库蚊体内黑化幼丝虫的比例最高(75.4％);而老龄致倦库蚊体内以滞育或畸形的幼丝虫比例最高(67.1％)。实验表明,蚊虫的免疫是影响幼丝虫发育的一个重要因素。免疫反应的强度在不同的蚊种间有显著差异,且随蚊虫日龄的增加而下降。

OBSERVATION ON THE EARLY DEVELOPMENT OF INOCULATED BRUGIA MALAY I MICROFILARIAE IN MOSQUITOES

This paper reports the early development and variation of incculate Brugia malayi microfilariae in 3 groups of mosquitoes,i.e.young Anopheles sinensis,young Culex quin-quefasciatus and old Cx.quinquefasciatus.Significant differences were observed among these groups.Sixty hours after inoculation,the percentage of normally developing filarial larvae in young An.sinensis was 72.3%;the percentage of melanized microfilarise in young Cx.quinquefasciatus was 75.4% and the percentage of filarial larvae which deve-loped abnormally or remained in dispause status in old Cx.quinquefasciatus was 67.1%,each being much higher than that in the other groups.It was suggested that the immune competence of the mosquitces had influence upen the filarial development.The intensity of the immune response not only varied with the species,but also diminished with the aging of mosquitces