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| 膳食诱导肥胖小鼠生殖功能变化的试验研究 | |
| 引用本文： | 张颖花,翟玲玲,张春东,白英龙,白霞,宿文辉,邓洁.膳食诱导肥胖小鼠生殖功能变化的试验研究[J].现代预防医学,2011,38(16):3179-3181. |
| 作者姓名： | 张颖花 翟玲玲 张春东 白英龙 白霞 宿文辉 邓洁 |
| 作者单位： | 1. 中国医科大学公共卫生学院,沈阳,110001 2. 中国医科大学临床医学系七年制 3. 中国医科大学基础医学院 |
| 摘 要： | 目的]探讨肥胖倾向(DIO)、抵抗和对照小鼠高脂饮食后性腺,睾丸精子数量、活动度的变化情况。方法]小鼠高脂膳食19周,分离睾丸、附睾和精囊腺,并称重,检测精子活动度和精子数量。结果]实验19周末,DIO组小鼠睾丸和附睾系数显著低于对照组小鼠;DIO小鼠的精子活动度显著低于对照组小鼠。结论]长期肥胖可能影响小鼠生殖器官的发育,影响小鼠精液品质。 |
| 关 键 词： | 肥胖 生殖 膳食诱导 |
STUDY ON THE CHANGE OF REPRODUCTIVE FUNCTION CAUSED BY OBESITY |
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| ZHANG Ying-hua,ZHAI Ling-ling,ZHANG Cun-dong,et al..STUDY ON THE CHANGE OF REPRODUCTIVE FUNCTION CAUSED BY OBESITY[J].Modern Preventive Medicine,2011,38(16):3179-3181. | |
| Authors: | ZHANG Ying-hua ZHAI Ling-ling ZHANG Cun-dong |
| Institution: | ZHANG Ying-hua,ZHAI Ling-ling,ZHANG Cun-dong,et al.(School of Public Health,Chinese Medical Sciences University,Shenyang 110001,China) |
| Abstract: | Objective]To study the change of gonad,the number and activity of sperm caused by obesity.Methods]High-fat diet was given in 19w. Testis,epididymis,and seminal vesicles were isolated and weighed,and the number and activity of sperm were detected.Results]In 19w,the testis and epididymis of DIO mice were significantly lower than the control mice. Sperm activity of DIO mice was significantly lower than control mice.Conclusion]Obesity may affect the development of reproductive organs in mice,and affect sper... |
| Keywords: | Obesity Reproduction Dietary guide |
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