| 磷酸肌酸钠对手足口病患儿心肌保护作用 |
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| 引用本文： | 李荣. 磷酸肌酸钠对手足口病患儿心肌保护作用[J]. 现代预防医学, 2011, 38(21): 4383-4384 |
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| 作者姓名： | 李荣 |
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| 作者单位： | 河南省开封市儿童医院药械科,开封,475000 |
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| 摘 要： | [目的]探讨磷酸肌酸钠对手足口病患儿心肌的保护作用。[方法]选取某院门诊收入手足口病区治疗的200例手足口病的患儿,随机分为对照组与实验组,每组各100例,对照组给予常规抗病毒、抗感染、解热及其他对症支持治疗,试验组在常规治疗的基础上给予磷酸肌酸钠治疗,2组治疗共1周。比较2组患者治疗前后的血清心肌肌钙蛋白I(cTnI)、磷酸肌酸激酶同工酶(CK-B)、乳酸脱氢酶同工酶(LDH-)变化情况。[结果](1)cTnI:试验组在治疗后为(0.54±0.12)mg/L,对照组在治疗后为(0.98±0.16)mg/L;(2)CK-MB:试验组在治疗后为(27.6±12.3)U/L,对照组在治疗后为(34.9±7.6)U/L;(3)LDH-1:试验组在治疗后为(52.1±13.4)U/L,对照组在治疗后为(71.6±13.5)U/L。3项指标均经t检验,P值均﹤0.05,差异有统计学意义。[结论]磷酸肌酸钠对手足口病患儿的心肌保护作用疗效确切,能较好的降低血清心肌酶的浓度,避免心肌损害。
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| 关 键 词： | 磷酸肌酸钠 手足口病 心肌保护 |
THE MYOCARDIAL PROTECTION FUNCTION OF ACID SODIUM PHOSPHATE IN THE HAND-FOOT-AND-MOUTH DISEASE CHILDREN |
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| LI Rong. THE MYOCARDIAL PROTECTION FUNCTION OF ACID SODIUM PHOSPHATE IN THE HAND-FOOT-AND-MOUTH DISEASE CHILDREN[J]. Modern Preventive Medicine, 2011, 38(21): 4383-4384 |
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| Authors: | LI Rong |
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| Affiliation: | LI Rong.(Drug and Equipment Section of Children's Hospital in Kaifeng City,Kaifeng 475000,China) |
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| Abstract: | [Objective]To study the function of creatine phosphate sodium in the myocardial protection of hand-foot-and-mouth disease children.[Methods]Chose 200 hand-foot-and-mouth disease children in our hospital,who were randomly divided into control group and experimental group.The control group was dealt with conventional antivirus,anti-infection,antipyretic and other symptomatic support treatment,the patients in the experimental group based on routine treatment were given acid sodium phosphate treatment.Compared ... |
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| Keywords: | Acid sodium phosphate muscle Hand-foot-and-mouth disease Myocardial protection |
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