| 血清及支气管肺泡灌洗液中细胞因子在急性呼吸窘迫综合症中的意义 |
| |
| 引用本文： | 张晓调. 血清及支气管肺泡灌洗液中细胞因子在急性呼吸窘迫综合症中的意义[J]. 现代预防医学, 2011, 38(16): 3383-3384,3389 |
| |
| 作者姓名： | 张晓调 |
| |
| 作者单位： | 温州医学院附属第三医院,瑞安,325200 |
| |
| 摘 要： | [目的]探讨血清及支气管肺泡灌洗液中细胞因子IL-8、IL-6及其受体IL-6R在急性呼吸窘迫综合症中的意义。[方法]连续纳入入住我院呼吸内科病房患者45人,分为3组:甲组:ARDS患者,乙组:有ARDS高危因素48h内发生ARDS,丙组:有ARDS高危因素但未发生ARDS。测量每个病人血浆及肺泡灌洗液中上述各细胞因子浓度,并比较3组间的差异。[结果]甲组肺泡灌洗液中的IL-6r浓度显著高于乙组及丙组(188±61vs.89±29和80±26;P﹤0.05),而乙组肺泡灌洗液中的IL-6浓度高于甲组及丙组(1130±998vs.313±22和531±401;P﹤0.05)。而血浆中的各种细胞因子在3组中未见明显差异。[结论]IL-6在ARDS发生的早期起重要的作用,可能是早期的一个启动因子,而IL-8在人类ARDS中的作用尚需进一步研究。
|
| 关 键 词： | 细胞因子 急性呼吸窘迫综合症 肺泡灌洗液 IL-6 IL-8 |
SERUM AND BRONCHOALVEOLAR LAVAGE FLUID CYTOKINES IN ACUTE RESPIRATORY DISTRESS SYNDROME IN THE SENSE |
| |
| ZHANG Xiao-diao. SERUM AND BRONCHOALVEOLAR LAVAGE FLUID CYTOKINES IN ACUTE RESPIRATORY DISTRESS SYNDROME IN THE SENSE[J]. Modern Preventive Medicine, 2011, 38(16): 3383-3384,3389 |
| |
| Authors: | ZHANG Xiao-diao |
| |
| Affiliation: | ZHANG Xiao-diao.(The Third Affiliated Hospital,Wenzhou Medical College,Ruian 325200,China) |
| |
| Abstract: | [Objective]To investigate the serum and bronchoalveolar lavage fluid cytokines IL-8,IL-6 and its receptor IL-6R in patients with acute respiratory distress syndrome in significance.[Methods]Consecutive into the respiratory medical ward of our hospital stay 45 patients were divided into three groups:Group A:ARDS patients,Group B:There are risk factors for ARDS within 48 hours of ARDS,and Group C:There are risk factors for ARDS but did not happen ARDS. The concentrations of the above cytokines in the plasma a... |
| |
| Keywords: | Cytokines Acute respiratory distress syndrome Lavage fluid IL-6 IL-8 |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
