| 咬合创伤牙髓组织中CGRP免疫阳性纤维的变化 |
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| 引用本文： | 郝作琦,刘洪臣,朱美玲,段利军. 咬合创伤牙髓组织中CGRP免疫阳性纤维的变化[J]. 口腔颌面修复学杂志, 2001, 2(2): 43-45 |
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| 作者姓名： | 郝作琦 刘洪臣 朱美玲 段利军 |
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| 作者单位： | 解放军军医进修学院 |
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| 基金项目： | 全军医药卫生科研基金课题 编号 96M－138 |
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| 摘 要： | 目的：探讨胶合创伤对牙髓组织中降钙素基因相关肽（CGRP）的影响。方法：利用免疫组织化学方法,观察大鼠牙齿在咬合创伤后1天、3天、7天、15天、1个月等不同实验期牙髓组织中CGRP免疫阳性纤维的变化。结果：咬合创伤引起大鼠牙髓组织中CGRP免疫反应阳性纤维出现形态、分布、密度的改变。结论：咬合创伤可使牙髓组织中的神经末梢释放CGRP、CGRP可能参与了创伤所致的牙髓炎症及修复过程。
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| 关 键 词： | 咬合创伤 牙髓组织 降钙素基因相关肽 |
| 文章编号： | 1009-3761(2001)02-0107-03 |
| 修稿时间： | 2001-02-06 |
Effect of CGRP immunoreactive nerve fibers in pulpal tissue of traumatic occlusion molar |
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| HAO Zuo-Qi,LIU Hon g-Chen,ZHU Mei-Ling,DUAN Li-Jun.. Effect of CGRP immunoreactive nerve fibers in pulpal tissue of traumatic occlusion molar[J]. Chinese Journal of Prosthodontics, 2001, 2(2): 43-45 |
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| Authors: | HAO Zuo-Qi LIU Hon g-Chen ZHU Mei-Ling DUAN Li-Jun. |
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| Abstract: | Objective: To study the effect of clactionin gene-related peptide (CGRP) in pulpal tissue by traumatic occlusion. Methods: To observe the change of CGRP- immunoreactive nerve fibres in the pulpal tissue of rat by traumatic occlusion at different observation of 1 day, 3 days, 7 days, 15 days and 30 days with immunohistochemical method. Results: The changes of CGRP- immunoreactive nerve fibres in morphology, distribution, and density were induced by traumatic occlusion in pulpal tissue of rat. Conclusions: Traumatic occlusion may lead to the release of CGRP from the pulp nervous terminals, and CGRP may play a role in the progress of pulpal inflammation and repair. |
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| Keywords: | traumatic occlusion pulpal tissue CGRP |
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