我国一些地区人血清的虫媒病毒抗体调查

本文调查了28个省、市、自治区的人血清对18种虫媒病毒抗原的血凝抑制抗体,发现我国广大地区主要存在乙组虫媒病毒,但也存在甲组和布尼安病毒的可能。甲组病毒的抗体阳性数占总阳性数的16.7%(58/347),新疆、青海、黑龙江、山西、福建、甘肃省占甲组虫媒病毒抗体阳性数的84%。布尼安病毒中特别是Aino病毒的抗体阳性率较高,占总阳性数的12.7%(45/347),黑龙江8/10人阳性,其HI滴度都大于1/80,最高为1/1280,平均滴度为1/320,黑龙江、新疆、福建、北京占布尼安总阳性数的70%。乙组虫媒病毒则以乙脑为主。但其它病毒的抗体如Zika、 Kunjin的抗体阳性也很高,故推测我国除已知有乙脑、森脑、登革热外,尚有其它乙组虫媒病毒存在的可能。

Arbovirus Antibody Survey of Human Sera in China

347 samples of human sera collected from different parts of China (except Tibct and Taiwan) were tested with hemagglutinationinhibition test against 18 antigens of Arboviruses including group A (Alphavrus): VEE,WEE, SF,GETAH, CHIK, SINDBIS; Group B (Flavivirus): JE, WN,DEN-2, SEPIK, ZIKA, KUNJIN, KFD, TEMBUSU, POWASSAN, Langet; Bunyamwera supergroup (Simbu group): AINO, INGWAVUMA. Sera were found to have antibodies not only against group B but also against group A and Bunyamwera supergroup arboviruses, The result indicated that group B arboviruses were prevalent in China, especially JE. But Kunjin and Zika viruses were first discovered to have a high prevalence rate especially ia Xinjiang and Qinghai areas. Group A arbovirus was not as prevalent as group B but there is still a sera positive rate of 58/347 (16.7%).Bunyamwera supergroup arbovirus antibody was first discovered in China. It is very interesting to find that there is a high prevalence rate against Aino virus, especiially in Heilongjiang Province, 8/10 human sera were positive, the HI titer was 1/80-1/1280 with an average titer of 1/320. The results showed that there are probably group A, Bunyamwera supergroup and other group B arboviruses in addition to JE DEN RSSE in China.