Chemotactic attraction of infective hookworm larvae ofAncylostoma caninum by a dog serum factor |
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Authors: | J. C. M. Vetter J. Vingerhoed E. Schoeman H. W. Wauters |
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Affiliation: | (1) Instituut voor Wetenschappelÿk Onderzoek Vakgroep Parasitologie, Universiteit van Amsterdam, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands |
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Abstract: | Infective hookworm larvae ofAncylostoma caninum showed chemotaxis on agar plates in a dog serum gradient. This chemotactic behaviour remain unaltered using an ultrafiltrated serum fraction with a molecular weight less than 500. Gelfiltration of this ultrafiltrated fraction revealed a factor with a molecular weight of 480 causing chemotaxis. The chemotactic activity of the factor was destroyed after a pronase treatment. We conclude that the factor could be a polypeptide. |
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