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党参、黄芪对实验性心肌缺血大鼠心电图影响的比较
引用本文:张晓丹,佟欣,刘琳,朱英淑.党参、黄芪对实验性心肌缺血大鼠心电图影响的比较[J].中草药,2003,34(11):1018-1019.
作者姓名:张晓丹  佟欣  刘琳  朱英淑
作者单位:哈尔滨商业大学,药学院,黑龙江,哈尔滨,150076
摘    要:目的 比较党参与黄芪提取物对实验性心肌缺血大鼠的保护作用。方法 采用垂体后叶素(Pit)法建立心肌缺血动物模型,以Ⅱ导联心电图T波和S—T段位移及心率的变化为指标,观察党参和黄芪对实验性心肌缺血大鼠的保护作用。结果 黄芪和党参均可减轻实验性心肌缺血大鼠心电图的T波抬高,并能减慢心率,但对心电图S—T段的位移无明显作用,并且党参减轻T波抬高的效果强于黄芪,而减慢心率的作用弱于黄芪。结论 党参和黄芪均对Pit致实验性心肌缺血起明显保护作用。

关 键 词:党参  黄芪  心肌缺血  心电图
文章编号:0253-2670(2003)11-1018-03
收稿时间:2003/1/27 0:00:00
修稿时间:2003年1月27日

Comparison of Radix Codonopsis and Radix Astragali on ECG of experimental myocardial ischemia rats
ZHANG Xiaodan,TONG Xin,LIU Lin and ZHU Yingshu.Comparison of Radix Codonopsis and Radix Astragali on ECG of experimental myocardial ischemia rats[J].Chinese Traditional and Herbal Drugs,2003,34(11):1018-1019.
Authors:ZHANG Xiaodan  TONG Xin  LIU Lin and ZHU Yingshu
Institution:Pharmaceutical Department of Harbin Commercial University, Harbin 150076, China;Pharmaceutical Department of Harbin Commercial University, Harbin 150076, China;Pharmaceutical Department of Harbin Commercial University, Harbin 150076, China;Pharmaceutical Department of Harbin Commercial University, Harbin 150076, China
Abstract:Object To compare the effects of Radix Codonopsis (RC) and Radix Astragali (RA) on ECG of experimental myocardial ischemia rats. Methods The model of myocardia ischemia was made by injection of pituitrin (Pit) in rats. The changes of ECG were observed with three parameters, viz. the heart rate, the locomotions of T wave and S T section. Results Both RC and RA can decrease the run up of T wave in ECG of rats with experimental myocardial ischemic injury in which RC is superior to RA. While RA has stronger effect on the slowering of the heart rate than RC.Conclusion Both RC and RA have protective effect on experimental myocardial ischemic injury induced by Pit.
Keywords:Radix Codonopsis (RC)  Radix Astragali (RA)  myocardial ischemia  ECG  
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