血管内超声联合雷帕霉素洗脱支架在冠心病合并糖尿病患者治疗中的效果

目的分析在冠心病合并糖尿病患者中采取血管内超声联合雷帕霉素洗脱支架的治疗效果。方法80例冠心病合并糖尿病患者,采用随机数字表法分为对照组和观察组,每组40例。观察组患者采用血管内超声联合雷帕霉素洗脱支架治疗,对照组患者采取单纯雷帕霉素洗脱支架治疗。比较两组患者围术期指标(手术时间、术中出血量、住院时间),手术前后狭窄程度与最小血管直径,术后并发症发生情况。结果观察组手术时间(51.43±6.21)min长于对照组的(30.28±5.54)min,差异具有统计学意义(t=16.074,P=0.000<0.05)。两组术中出血量、住院时间比较差异无统计学意义(P>0.05)。手术前,两组狭窄程度、最小血管直径比较差异无统计学意义(P>0.05);手术后,两组狭窄程度、最小血管直径均较手术前明显改善,且观察组改善幅度大于对照组,差异具有统计学意义(P<0.05)。观察组术后并发症发生率7.50%(3/40)低于对照组的25.00%(10/40),差异具有统计学意义(χ²=4.501,P=0.034<0.05)。结论血管内超声联合雷帕霉素洗脱支架应用于冠心病合并糖尿病患者治疗中,能够提升支架置入的治疗效果,降低并发症发生几率。

Effect of intravascular ultrasound combined with rapamycin-eluting stent in the treatment of coronary heart disease complicated with diabetes mellitus

Objective To analyze the therapeutic effect of intravascular ultrasound combined with rapamycin-eluting stent in the treatment of coronary heart disease complicated with diabetes mellitus.Methods A total of 80 cases of coronary heart disease complicated with diabetes mellitus were divided into control group and observation group according to random numerical table,with 40 cases in each group.The observation group was treated with intravascular ultrasound combined with rapamycin-eluting stent,and the control group was treated with rapamycin-eluting stent only.The perioperative indicators(operation time,intraoperative blood loss and hospitalization time),degree of stenosis and minimum vessel diameter before and after operation,and occurrence of postoperative complications were compared between the two groups.Results The operation time(51.43±6.21)min of the observation group was longer than(30.28±5.54)min of the control group,and the difference was statistically significant(t=16.074,P=0.000<0.05).There was no statistically significant difference in intraoperative blood loss and hospitalization time between the two groups(P>0.05).Before operation,there was no statistically significant difference in degree of stenosis and minimum vessel diameter between the two groups(P>0.05).After operation,the degree of stenosis and minimum vessel diameter of the two groups were obviously better than those before operation,and the observation group improved more than the control group.All the difference was statistically significant(P<0.05).The incidence of postoperative complications 7.50%(3/40)of the observation group was lower than 25.00%(10/40)of the control group,and the difference was statistically significant(χ~2=4.501,P=0.034<0.05).Conclusion Combination of intravascular ultrasound and rapamycin-eluting stent in patients with coronary heart disease and diabetes mellitus can improve the effect of stent implantation and reduce the incidence of complications.