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Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs
Authors:Clyde Dapat  Yasushi Suzuki  Reiko Saito  Yadanar Kyaw  Yi Yi Myint  Nay Lin  Htun Naing Oo  Khin Yi Oo  Ne Win  Makoto Naito  Go Hasegawa  Isolde C. Dapat  Hassan Zaraket  Tatiana Baranovich  Makoto Nishikawa  Takehiko Saito  Hiroshi Suzuki
Abstract:In 2007 and 2008 in Myanmar, we detected influenza viruses A (H3N2) that exhibited reduced sensitivity to both zanamivir and amantadine. These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2.
Keywords:Influenza A virus   H3N2 subtype   zanamivir   amantadine   antiviral drug resistance   viruses   Myanmar   expedited   dispatch
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