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The impact of cancer treatment on reproductive health in young women
Authors:Tukur A. Jido  Margaret E. Cruickshank
Affiliation:1. Institute for Partnerships to Eliminate Health Disparities University of South Carolina, Columbia, South Carolina, USA;2. Palmetto Healthy Start Palmetto Health, Columbia, South Carolina, USA;1. Center for Spine Health, Cleveland Clinic, Cleveland, OH, USA;2. School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA;3. Department of Neurosurgery, Cleveland Clinic, Cleveland, OH, USA;4. Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA;5. Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD;6. Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA;7. Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA
Abstract:The diagnosis of cancer can precipitate a re-evaluation of life at all ages. In children, adolescents and young adults, a cancer diagnosis and its treatment poses specific challenges that can affect all aspects of reproductive health resulting in considerable physical, psychological and psychosexual burden. Improved survival means that this cohort of patients is expanding and with an improving life span, the resulting morbidity is also extended. The demands of this group of patients are often not fully integrated in the operational functions of the health service with considerable variation in care. This review discusses the common reproductive morbidities amongst survivors of childhood, adolescent and young adult cancer whilst planning, delivering and following cancer treatment. This includes the current issues on the assessment of ovarian reserve and preservation of fertility.
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