Diagnostic approach to lymphoid lesions of major salivary glands |
| |
| Authors: | Gary L. Ellis |
| |
| Affiliation: | 1. Department of Laboratory Medicine, St Michael''s Hospital, Toronto, Canada M5B 1W8;2. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada M5S 1A5;3. Zane Cohen Clinical Research Centre, Mount Sinai Hospital, Toronto, Canada M5G 1X5;4. Division of General Surgery, Mount Sinai Hospital, Toronto, Canada M5G 1X5;5. Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada M5G 1X5;6. Department of Pathology, University Health Network, Toronto, Canada M5G 2C4;1. Department of Immunology, Flinders Medical Centre and Flinders University, SA Pathology, Bedford Park, 5042, South Australia, Australia;2. Flinders Proteomic Facility, School of Medicine, Flinders University, Australia;1. Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH 44195;2. Cedars-Sinai Medical Center, Los Angeles, CA, 90048;3. Targu Mures University of Medicine and Pharmacy, Targu Mures, 540139, Romania;4. Mexican Oncology Hospital, Mexico City, DF 06720, Mexico;5. Instituto Nacional de Cancerologia (Mexico), Mexico City DF 14080, Mexico;6. Medical College of Wisconsin, Milwaukee, 53226, WI;7. The University of Texas MD Anderson Cancer Center, Houston, 77030, TX |
| |
| Abstract: | Among lesions of the major salivary glands (parotid, submandibular, and sublingual glands), those with a prominent lymphoid component are encountered frequently in the surgical pathology laboratory and range from reactive lesions to benign and malignant neoplasms. A majority of these lymphoid lesions have a co-mingled epithelial component, which also ranges from benign to malignant. As a result, many of these lesions have similar and overlapping histopathologic features, and attention to details, sometimes subtle, is required to accurately distinguish one from another. This review will discuss these lymphoid-epithelial lesions of major salivary glands, with emphasis on features that help in the differential diagnosis. Entities discussed include lymphoepithelial sialadenitis, HIV-associated salivary gland disease, extranodal marginal zone B-cell lymphoma, lymphoepithelial carcinoma, lymphadenoma, sebaceous lymphadenocarcinoma, chronic sclerosing sialadenitis, and Warthin tumour. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
