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夏枯草对自发高血压大鼠血压的影响研究
引用本文:游淑梅,朱玉婷. 夏枯草对自发高血压大鼠血压的影响研究[J]. 海峡药学, 2011, 23(3): 37-38
作者姓名:游淑梅  朱玉婷
作者单位:浙江省皮肤病防治研究所,德清,313207
摘    要:目的观察夏枯草水溶性成分对高血压大鼠血压的影响,为高血压治疗提供新的思路。方法 10只自发性高血压大鼠随机分为2组,每组5只:(1)高血压对照组(2)夏枯草水溶性成分组。每天通过灌胃法分别给予夏枯草水溶性成分,每隔一段时间用大鼠尾动脉血压无创测量分析系统测量大鼠动脉收缩压一次,共6次。结果给药后,夏枯草水溶性成分组的动脉收缩压与对照组相比显著下降。结论夏枯草水溶性成分可以有效降低自发性高血压大鼠的动脉血压。

关 键 词:高血压  夏枯草  水溶性成分  模型  动物

Effect of Common Selfheal Fruit-Spike on blood pressure in spontaneously hypertensive rates
YOU Shu-mei,ZHU Yu-ting. Effect of Common Selfheal Fruit-Spike on blood pressure in spontaneously hypertensive rates[J]. Strait Pharmaceutical Journal, 2011, 23(3): 37-38
Authors:YOU Shu-mei  ZHU Yu-ting
Affiliation:(Zhejiang Institute of Dermatology,Deqing 313207,China)
Abstract:OBJECTIVE To investigate the effect of Common Selfheal Fruit-Spike in reducing the blood pressure of the spontaneously hypertensive rats(SHR).METHODS The 10 SHR were randomly divided into 2 groups(1)SHR control group(2) Common Selfheal Fruit-Spike group.Every day each rat′s systolic blood pressure(SBP) was measured with the tail-cuffmethod.RESULTS After hours,SBP of high dose of Common Selfheal Fruit-Spike.group was reduced significantly compared with that control group.CONCLUSION Common Selfheal Fruit-Spike can reduce the blood pressure of the spontaneously hypertensive rats significantly.
Keywords:Hypertension  Common Selfheal Fruit-Spike  Hydrosoluble composition  Odels  Animal
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