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黄金分割法优选半枝莲提取工艺
引用本文:刘君焱,王玉蓉,刘益.黄金分割法优选半枝莲提取工艺[J].中国中药杂志,2008,33(8):896-899.
作者姓名:刘君焱  王玉蓉  刘益
作者单位:北京中医药大学中药学院,北京,100102
摘    要:目的:探讨在半枝莲提取工艺过程将黄金分割法作为筛选方法的可行性。方法:以野黄芩苷和总黄酮含量为考察指标,用黄金分割法和等距法筛选提取半枝莲的乙醇浓度的水平范围,以正交试验验证。结果:半枝莲的最佳提取工艺为15倍70%乙醇回流提取,提取3次,每次1 h。结论:将黄金分割法用于半枝莲提取工艺研究基本可行,可作为中药提取工艺的预筛选方法。

关 键 词:黄金分割法  等距法  正交实验设计  半枝莲  提取工艺
文章编号:1001-5302(2008)08-0896-04
收稿时间:2007/7/20 0:00:00
修稿时间:2007年7月20日

Optimizing extraction process of Scutellaria barbata by golden section method
LIU Jun-yan;WANG Yu-rong;LIU Yi.Optimizing extraction process of Scutellaria barbata by golden section method[J].China Journal of Chinese Materia Medica,2008,33(8):896-899.
Authors:LIU Jun-yan;WANG Yu-rong;LIU Yi
Institution:College of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China. 24liujunyan@yahoo.com.cn
Abstract:Objective:To probe into the feasibility of golden section method in the optimization of the extraction process of Scutellaria barbata.Method:With the determination of the content of scutellarin and total flavonoids,selecting the range of alcohol concentration in the extraction of S.barbata was determined by the golden section method and method of equal interval,and validated it by orthogonal design.Result:The best extraction technique is that extract 3 times with 15 times of the alcohol which concentration is 70%,and each time for 1 h.Conclusion:Applying golden section method in the extraction of S.barbata is practical,which as a method of preliminary trial,indicates that golden section method can also be applied into the field of optimization of extraction process of traditional Chinese medicine.
Keywords:golden section method  method of equal interval  orthogonal design  Scutellaria barbata  extraction process
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