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Comparative efficacy of platidiam and carboplatin against tumor cells of human ovarian primary carcinomas
Authors:I. K. Sviridova  N. S. Sergeeva  V. I. Chissov  V. A. Kirsanova  A. V. Babarina  E. G. Novikova  G. A. Obrubova
Affiliation:(1) P. A. Hertzen Research Oncological Institute, Moscow
Abstract:The efficacies of platidiam and carboplatin against human ovarian cancer cells (21 samples) were compared usingthe in vitro MTT test. Sampling analysis showed a some-what higher mean activity of carboplatin in comparison with platidiam in the dose range equivalent to 0.1 to 3.0 therapeutic doses. The efficacy of carboplatin was found to increase more rapidly with dosage build-up than that of platidiam. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No. 8, pp. 208–210, August, 1995
Keywords:experimental chemotherapy    human ovarian carcinoma cells    cytostatic doseeffect curves
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