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职业性接触锰对作业工人神经行为功能的影响
引用本文:郑玉新,周晓蓉,潘举升,马增荣,祝刚,甘为民,方梅芳,徐凌,薛敏,尹明根,陈敏珍,张寿林,何凤生.职业性接触锰对作业工人神经行为功能的影响[J].卫生研究,1999,28(4):198-199,202.
作者姓名:郑玉新  周晓蓉  潘举升  马增荣  祝刚  甘为民  方梅芳  徐凌  薛敏  尹明根  陈敏珍  张寿林  何凤生
作者单位:1. 中国预防医学科学院劳动卫生与职业病研究所,北京,100050
2. 江西新余钢铁公司防疫站
3. 江西南昌飞机制造公司职业病防治所;江西省工业卫生研究所
基金项目:中国预防医学科学院资助
摘    要:在对锰铁冶炼和电焊作业工人锰的累积暴露剂量评价的基础上,探讨了锰对工人的早期效应。结果发现,锰对工人神经系统功能的影响主要表现为手稳定度、反应速度、记忆力和注意力的下降,并且有随暴露剂量增加而行为功能改变严重的趋势。提示锰的累积暴露水平达1mg/m+3.年时,可能对工人神经系统产生早期亚临床改变。

关 键 词:  神经行为测试  累积暴露指数

Changes of neurobehavioral functions in workers exposed to manganese
Institute of Occupational Medicine,Chinese Academy of Preventive Medicine,Beijing ,China.Changes of neurobehavioral functions in workers exposed to manganese[J].Journal of Hygiene Research,1999,28(4):198-199,202.
Authors:Institute of Occupational Medicine  Chinese Academy of Preventive Medicine  Beijing  China
Institution:Institute of Occupational Medicine, Chinese Academy of Preventive Medicine, Beijing 100050, China.
Abstract:The aim of this study was to assess the neurotoxic effects associated with the level of airborne manganese in the work place.A cumulative exposure index(CEI)was calculated for each subject.The neurobehavioral test battery,in terms of choosing reaction time,finger tapping,digit symbol,stylus in hole,Benton visual retention and Santa Ana dexterity was applied in the study.The manganese exposed workers had slower motor and response speed,poorer visuomotor coordination and steadiness.There was a doseresponse relationship tendency between the cumulative exposure index and the behavioral function.Hence the neurobehavioral test may be a sensitive method in detecting early changes in motor and cognitive function among manganeseexposed workers.The study also demonstrates that the cumulative exposure of manganese abuout 1mg/m3 per year may induce subclinical signs of intoxication.
Keywords:manganese  neurobehavioral test  cumulative exposure index
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